Semicarbazone
Semicarbazones are organic chemical compounds that contain the grouping C = N – NH – CO – NH 2 as a functional group .
Manufacturing
Semicarbazones can be produced from semicarbazide or its salts and carbonyl compounds (more precisely aldehydes and ketones ) with elimination of water :
use
Similar to hydrazones and oximes , semicarbazones were previously of analytical importance, as their melting point enables the underlying carbonyl compound to be identified. Furthermore, semicarbazones can be used for the isolation and purification of carbonyl compounds, since semicarbazones can easily be hydrolytically cleaved again when exposed to dilute acids.
A semicarbazone used pharmacologically as an antiseptic is nitrofural .
Individual evidence
- ↑ Joachim Buddrus, Bernd Schmidt: Fundamentals of organic chemistry. 5th edition, de Gruyter Verlag, Berlin, 2015, p. 485, ISBN 978-3-11-030559-3 .
- ↑ Science-Online-Lexika: Entry on "Semicarbazone" in the Lexikon der Chemie. Retrieved June 9, 2010.