Spidroin 1
| Spidroin-1 | ||
|---|---|---|
| other names |
Dragline silk fibroin 1, Major ampullate Spidroin 1, MaSp-1 |
|
| Mass / length primary structure | 748 amino acids , 60,585 Da | |
| Identifier | ||
| External IDs | ||
| Orthologue | ||
| Nephila clavipes | Araneus bicentenarius | |
| Entrez | NV | NV |
| UniProt | P19837 | P46802 |
| PubMed search | NV |
NV
|
Spidroin 1 is a fiber protein from the silk of the spider Nephila clavipes . It is related to fibroin from the silkworm .
properties
Spidroin 1 occurs in all types of spider fibers. The middle part of the amino acid sequence consists of tandem repeats . It has the characteristic sequence motif glycine -glycine- tyrosine , like spidroin 2 . Spidroin 1 has dityrosine and 3,4-dihydroxyphenylalanine as unusual amino acids , which are formed after translation through oxidation of the protein.
literature
- M. Andersson, J. Johansson, A. Rising: Silk Spinning in Silkworms and Spiders. In: International journal of molecular sciences. Volume 17, number 8, August 2016, p. 1290, doi : 10.3390 / ijms17081290 , PMID 27517908 , PMC 5000687 (free full text).
Individual evidence
- ^ AD Malay, K. Arakawa, K. Numata: Analysis of repetitive amino acid motifs reveals the essential features of spider dragline silk proteins. In: PloS one. Volume 12, number 8, 2017, p. E0183397, doi : 10.1371 / journal.pone.0183397 , PMID 28832627 , PMC 5568437 (free full text).
- ↑ JR dos Santos-Pinto, G. Lamprecht, WQ Chen, S. Heo, JG Hardy, H. Priewalder, TR Scheibel, MS Palma, G. Lubec: Structure and post-translational modifications of the web silk protein spidroin-1 from Nephila spiders. In: Journal of proteomics. Volume 105, June 2014, pp. 174-185, doi : 10.1016 / j.jprot.2014.01.002 , PMID 24434585 .