Spidroin 2
| Spidroin-2 | ||
|---|---|---|
| other names |
Dragline silk fibroin 2, Major ampullate Spidroin 2, MaSp-2 |
|
| Mass / length primary structure | 627 amino acids , 54,184 Da | |
| Identifier | ||
| External IDs | ||
Spidroin 2 is a fiber protein from the silk of the spider Nephila clavipes . It is related to fibroin from the silkworm .
properties
Spidroin 2 occurs in all types of spider fibers. The large middle part of the amino acid sequence consists partly of repeats. Spidroin 2 has the characteristic sequence motif glycine-glycine - tyrosine , just like spidroin 1 , and also the motifs glycine- phenylalanine (GP) and glutamine-glutamine (QQ). Spidroin 2 is phosphorylated .
literature
- M. Andersson, J. Johansson, A. Rising: Silk Spinning in Silkworms and Spiders. In: International journal of molecular sciences. Volume 17, number 8, August 2016, p., Doi : 10.3390 / ijms17081290 , PMID 27517908 , PMC 5000687 (free full text).
Individual evidence
- ↑ a b A. D. Malay, K. Arakawa, K. Numata: Analysis of repetitive amino acid motifs reveals the essential features of spider dragline silk proteins. In: PloS one. Volume 12, number 8, 2017, p. E0183397, doi : 10.1371 / journal.pone.0183397 , PMID 28832627 , PMC 5568437 (free full text).
- ↑ JR Santos-Pinto, HA Arcuri, G. Lubec, MS Palma: Structural characterization of the major ampullate silk spidroin-2 protein produced by the spider Nephila clavipes. In: Biochimica et Biophysica Acta . Volume 1864, number 10, 10 2016, pp. 1444-1454, doi : 10.1016 / j.bbapap.2016.05.007 , PMID 27208434 .