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Spiegler is the family name of the following people:
- Eduard Spiegler (1860–1908), Austrian dermatologist
- Eugen Spiegler (1883– ??), Austrian walker
- Franz Joseph Spiegler (1691–1757), South German baroque painter
- Gottfried Spiegler (1891–1970), Austrian hospital physicist and closest collaborator to Holzknecht in Vienna
- Hans Jacob Spiegler (1570/1580 - before 1658), painter from Württemberg
- Mark Spiegler , American agent
- Mordechai Spiegler (* 1944), Israeli soccer player
- Ralph Spiegler (* 1961), German local politician