Tetanolysin
| Tetanolysin | ||
|---|---|---|
| Identifier | ||
| Gene name (s) | tly | |
| External IDs |
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| Occurrence | ||
| Parent taxon | Clostridium | |
Tetanolysin is an exotoxin formed by the bacterium Clostridium tetani during anaerobic wound infections ( tetanus ) . In contrast to the more important tetanospasmin (the actual tetanus toxin), tetanolysin has a hemolytic effect . The protein has a molar mass of 55 kDa . It acts as a pore-forming toxin from the group of cholesterol- dependent cytolysins similar to streptolysin O and binds to cholesterol.
Individual evidence
- ↑ PA Keyel, ME Heid, RD Salter: Macrophage responses to bacterial toxins: a balance between activation and suppression. In: Immunologic research. Volume 50, Number 2-3, August 2011, pp. 118-123, doi : 10.1007 / s12026-011-8212-3 , PMID 21717083 .