Transdermal
The term transdermal (from Latin trans "through, through" and Greek derma "skin") is mostly used to describe the administration of medicinal substances for absorption (absorption) through the skin .
The main forms of administration available are transdermal patches . The prerequisite for transdermal absorption is a certain degree of lipophilic properties and a relatively small size of the active substance molecule . Examples of drugs are the opioid fentanyl in pain therapy , nicotine patches for smoking cessation , estrogens for hormone replacement therapy (HRT) and NO- releasing nitro compounds for the treatment of ischemic diseases such as angina pectoris , scopolamine for the treatment of kinetosis (travel sickness) and estrogen / gestagen-active ingredient combinations hormonal contraception .
Individual evidence
- ↑ Lüllmann et al .: Pharmacology and Toxicology . 15th edition. Thieme Verl. 2003.