Tyzzer's Disease

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The Tyzzer's disease (also Tyzzersche disease or shortly Tyzzer ) is determined by the bacterium Clostridium Piliforme (formerly as Bacillus piliformis hereinafter) caused. This bacterium was discovered and classified in 1917 by Ernest Edward Tyzzer (1875-1965), a professor at Harvard Medical School .

Pathogen

Clostridium piliforme has a wide host range . It infects rabbits , laboratory rodents , wild rodents , domestic animals, and several other non-rodent animals. Case reports have in common that mainly young animals are affected, or they were immunocompromised by another disease . The bacterium is apparently transmitted through the ingestion of water and food or through the animals' sleeping quarters.

Symptoms

The disease manifests itself in fatigue, reluctance to eat and diarrhea . It can also be symptom-free in older animals, but it can be peracute in young animals .

diagnosis

The diagnosis is usually made by examining the infected animal's liver with a light microscope .

treatment

literature

  • EE Tyzzer: A fatal disease of the Japanese waltzing mouse caused by a spore-bearing bacillus (Bacillus piliformis, N. SP.). In: J Med Res. 37, 1917, pp. 307-338.
  • KS Waggie, JE Wagner, ST Kelley: Naturally occurring Bacillus piliformis in guinea pigs. In: Lab Anim Sci. 36, 1986, pp. 504-506.

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