Uli Kazmaier

Uli Kazmaier

Uli Kazmaier (born January 17, 1960 in Bönnigheim ) is a German chemist. Since 2001 he has been Professor of Organic Chemistry at Saarland University .

Life

Uli Kazmaier studied chemistry in Stuttgart from 1979 to 1986 and received his doctorate in 1989 in the field of natural product synthesis under Ulrich Schmidt . This was followed by research stays at the University of Marburg with Manfred Reetz and at Stanford University with Barry M. Trost .

In 1992 he started his own research in the field of amino acid and peptide chemistry at the University of Heidelberg in the environment of Günter Helmchen . In 1997 he completed his habilitation in Heidelberg. After working as a private lecturer in Heidelberg between 1998 and 2001 and taking over a professorship at the University of Karlsruhe for Herbert Waldmann , he was offered a position at the University of Saarland. Since 2001 he has held the chair for organic chemistry there. He turned down calls to the Universities of Bayreuth (2000) and Heidelberg (2006).

Scientific work

Uli Kazmaier's research focuses on the one hand on the development of new synthesis methods and the synthesis of natural and active ingredients. In addition to organometallic reactions, primarily catalytic processes are used here.

Publications

Uli Kazmaier has published over 200 scientific publications, book chapters, books and magazine articles.

Works (selection)

Books

• Chemistry for pharmacists: Taking into account the GK Pharmazie . Together with Hans Peter Latscha and Helmut Klein. 5th edition, Springer, Heidelberg, 2002. ISBN 978-3-540-42755-1
• Chemistry for biologists . Together with Hans Peter Latscha and Helmut Klein. 3rd edition, Springer, Heidelberg, 2008. ISBN 978-3-540-78843-0
• Topics in Organometallic Chemistry - Transition Metal Catalyzed Enantioselective Allylic Substitution in Organic Synthesis . Springer, Berlin, Heidelberg, 2011. ISBN 978-3-642-22749-3 (editor's text)
• Organic chemistry - basic knowledge II . Together with Hans Peter Latscha and Helmut Klein. 7th edition, Springer, Heidelberg, 2016. ISBN 978-3-662-46179-2

Book contributions

• Diastereoselective Hydrogenations In: Houben-Weyl - Methods of Organic Chemistry E 21 (Stereoselective Synthesis) . Ed .: G. Helmchen, RW Hoffmann, J. Mulzer, E. Schaumann, Thieme, Stuttgart 1996 pp. 4239–4316.
• Cross Coupling Reactions via p-Allyl Intermediates In: Metal Catalyzed CC and CN Coupling Reactions . Ed .: A. de Meijere, F. Diederich, Wiley-VCH, Weinheim 2004. pp. 531-583.
• Chelate Enolate Claisen Rearrangements . In: Claisen Rearrangements . Ed .: M. Hiersemann, U. Nubbemayer, Wiley-VCH, Weinheim 2007, pp. 233-299.
• Metal Enolates as Synthones in Organic Chemistry . Together with D. Stolz. In: Patai - The Chemistry of Functional Groups Ed .: J. Zabicky, Wiley, New York 2009, pp. 355-409.
• Transition metal catalyzed reactions towards the synthesis of amino acids and peptides . In: Frontiers in Asymmetric Synthesis and Application of alpha-Amino Acids . Ed .: VA Soloshonok, K. Izawa, ACS Books, Washington 2009, pp. 157–176.
• Synthesis and Chemistry of a, b-Dehydroamino Acids . In: Amino Acids, Peptides and Proteins in Organic Chemistry Vol. 2 . (Ed .: AB Hughes), Wiley-VCH, Weinheim 2009, pp. 3-34.
• Cross-Coupling Reactions via p-Allylmetal Intermediates . Together with A, Bayer. In: Metal-Catalyzed Cross-Coupling Reactions and More , (Ed .: A. de Meijere, S. Bräse, M. Oestreich), Wiley-VCH, Weinheim 2014, pp. 926-994.

Magazine articles

• Internal Redox Catalyzed by Triphenylphosphine . Together with BM Trost. I J. Am. Chem. Soc. 1992, No. 114, pp. 7933-7935
• Synthesis of Unsaturated Amino Acids by [3,3] -Sigmatropic Rearrangement of Chelate-Bridged Glycine Ester Enolates . Angewandte Chemie 1994, No. 33, pp. 998-999.
• Synthesis of Chiral γ, δ-Unsaturated Amino Acids by Asymmetric Ester Enolate Claisen Rearrangement . Together with A. Krebs. Angewandte Chemie 1995, No. 34, 2012-2013.
• Chelated Enolates of Amino Acid Esters — Efficient Nucleophiles in Palladium-Catalyzed Allylic Substitutions . Together with FL Zumpe. Angewandte Chemie 1999, No. 38, pp. 1468-1470.
• Palladium-Catalyzed Allylic Alkylations without Isomerization — Dream or Reality? . Together with FL Zumpe. Angewandte Chemie 2000, No. 39, pp. 802-804
• Regio- and Stereoselective Rhodium-Catalyzed Allylic Alkylations of Chelated Enolates . Together with D. Stolz. Angewandte Chemie 2006, No. 45, pp. 3072-3075
• Highly Stereoselective Allylic Alkylations of Peptides . Together with J. Deska and A. Watzke. Angewandte Chemie 2006, No. 45, pp. 4855-4858
• Pretubulysin, a potent and chemically-accessible tubulysin precursor from Angiococcus disciformis . Together with A. Ullrich, Y. Chai et al. Angewandte Chemie 2009, No. 47, pp. 4422-4425
• A Straightforward Approach towards Cyclic Photoactivatable Tubulysin Derivatives . Together with J. Hoffmann. Angewandte Chemie 2014, No. 53, pp. 11356-11360.
• Total Syntheses and Biological Evaluation of Miuraenamides . Together with L. Karmann, K. Schulz et al. Angewandte Chemie 2015, No. 127, pp. 4502-4507

Web links

• Literature by and about Uli Kazmaier in the catalog of the German National Library
• Homepage of the Kazmaier working group at Saarland University.

Individual evidence

1. ↑ biography on uni-saarland.de.
2. ↑ Publications on uni-saarland.de.