Günter Helmchen

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Günter Helmchen (1998)

Günter Helmchen (born August 21, 1940 in Groß Lipke , district of Graetz (Wartheland) ) is a German chemist and was a professor at the Ruprecht-Karls-Universität Heidelberg .

Life

Helmchen grew up in the Hanover area . After graduating from high school, he studied chemistry at the University of Hanover and graduated in 1965 with Walter Theilacker on benzylic radicals . As a scholarship holder he then went to Zurich to the Swiss Federal Institute of Technology , where he received his doctorate in 1970 . His mentor was Vladimir Prelog , and his dissertation entitled Investigations into pseudo-asymmetric organic compounds was awarded the ETH Zurich medal. In 1972 Helmchen went to the University of Stuttgart , where he completed his habilitation in 1980 . In 1981 he accepted a professorship at the University of Würzburg . Since 1985 he has held Chair I for Organic Chemistry as a full professor for Organic Chemistry at the University of Heidelberg. Helmchen retired in 2008. His successor is Uwe Bunz . Helmchen has been a senior professor at Heidelberg University since 2011. The Heidelberg Academy of Sciences it belongs since 1998 as a full member.

Research area

Helmchen's main research areas are the synthesis of chiral compounds, especially natural products , and enantioselective catalysis . During his doctorate, Helmchen dealt with the nomenclature of chiral compounds. His work was incorporated into the CIP nomenclature that is common today . The first targeted production of pseudo-asymmetric connections with the coining of the term prochirality was published by Helmchen in 1972.

Helmet auxiliary

In the 1980s he developed the Helmchen synthesis, named after him, for the enantioselective synthesis of α-chiral carboxylic acids or β-chiral alcohols using the Helmchen auxiliary . In the later years enantioselective catalysis joined his interests. He was involved in the development of chiral phosphinooxazoline ligands , which are now known as PHOX ligands . While these ligands were used for catalysis with palladium , Helmchen later developed ligands and areas of application for the newly emerging field of regio- and enantioselective iridium catalysis, which he first published in 1997.

Publications

Helmchen published numerous articles in scientific journals and, in addition to working on other specialist chemical literature, was instrumental in the realization of the ten volumes of Houben-Weyl on the subject of stereoselective synthesis .

Awards

  • 1971 medal and prize from the ETH Zurich
  • 1979 Prize of the Friends of the University of Stuttgart for special scientific achievements
  • 1981 Karl Winnacker Scholarship
  • 1981 Prize for Chemistry from the Academy of Sciences in Göttingen
  • 1991 Fellowship Award Japanese Society for the Promotion of Science
  • 1997 Prelog medal and lecture from ETH Zurich
  • 2001 Horst Pracejus Prize from the Society of German Chemists

Others

A footpath in the immediate vicinity of the Organic Chemistry Institute of the University of Heidelberg is named "Günter-Helmchen-Allee" in his honor.

Web links

Individual evidence

  1. ↑ a b Chimia 1997 , 51 , 971-972.
  2. ^ Members of the HAdW since it was founded in 1909. Günter Helmchen. Heidelberg Academy of Sciences, accessed July 2, 2016 .
  3. ^ V. Prelog, G. Helmchen: Pseudoasymmetry in organic chemistry , in: Helv. Chim. Acta 1972 , 55 , 2581-2598.
  4. ↑ Reinhard Brückner: Reaction Mechanisms, 3rd edition, pp. 549–552, Spektrum Akademischer Verlag, Munich 2004 , ISBN 3-8274-1579-9 .
  5. ↑ M. Christmann, S. Bräse, D. Seebach : Asymmetric Synthesis , 2nd edition, pp. 3–9, Wiley-VCH, Weinheim, 2007 , ISBN 978-3527320936 .
  6. ↑ P. von Matt, O. Loiseleur, G. Koch, A. Pfaltz, C. Lefeber, T. Feucht, G. Helmchen: Enantioselective Allylic Amination with Chiral (Phosphino-oxazoline) Pd Catalysts in, Tetrahedron: Asymmetry 1994 , 5 , 573-584.
  7. ↑ G. Helmchen, A. Pfaltz: Phosphinooxazolines - A New Class of Versatile, Modular P, N-Ligands for Asymmetric Catalysis in, Accounts of Chemical Research 2000 , 33 , 336-345.
  8. ↑ JP Janssen: First Regio- and Enantioselective Alkylations of Monosubstituted Allylic Acetates Catalyzed by Chiral Iridium Complexes , in: Tetrahedron Lett. 1997 , 8025-8026.
  9. ↑ A. Dahnz, P. Dübon, M. Schelwies, R. Weihofen, G. Helmchen: iridium-catalyzed asymmetric allylic substitutions , in: Chemical Communications 2007 , 675-691.
  10. ↑ Map from strassen.openalfa.de accessed on December 15, 2019
personal data
SURNAME Helmchen, Günter
BRIEF DESCRIPTION German chemist and professor at the Ruprecht-Karls-Universität Heidelberg
DATE OF BIRTH August 21, 1940
PLACE OF BIRTH Groß Lipke , district of Grätz (Wartheland)