Remaining intrinsic secretion rate

The remaining self-secretion rate is the residual performance of the insulin- producing cells , which can be measured in particular by a C-peptide . This is impaired by the autoimmune process. As a rule, the remaining intrinsic secretion rate in diabetes mellitus does not fall to zero immediately, but only after several years. Only in pancreatic diabetes mellitus (e.g. removal of the pancreas ) is the intrinsic secretion rate immediately reduced to zero.

The residual secretion influences the insulin dose and means that after the initial manifestation only a small part of the total requirement has to be replaced. With the advancing sinking of the Langerhans Islands , the natural secretion rate decreases.

However, the pancreas in connection with the supplied insulin can also be responsible for inexplicable hypoglycaemia , if a low blood sugar usually blocks the release of glycogen and promotes an additional release of insulin.

This article is about a health issue. It is not used for self-diagnosis and does not replace a diagnosis by a doctor. Please note the information on health issues !