WASF1

from Wikipedia, the free encyclopedia
first member of the Wiskott-Aldrich syndrome proteins
other names
  • first member of the WASP proteins
  • Protein WAVE1
  • Protein 1 containing verproline homologous domain

Available structural data : 3P8C , 4N78

Properties of human protein
Mass / length primary structure 61.7 kDa / 559 amino acids
Identifier
Gene names WASF1 KIAA0269, SCAR1, WAVE1
External IDs
Orthologue
human House mouse
Entrez 8936 House mouse
Ensemble ENSG00000112290 ENSMUSG00000019831
UniProt Q92558 Q8R5H6
Refseq (mRNA) NM_001024934 NM_031877
Refseq (protein) NP_001020105 NP_114083
Gene locus Chr 6: 110.1 - 110.19 Mb Chr 10: 40.88 - 40.94 Mb
PubMed search 8936 House mouse

The first member of the Wiskott-Aldrich syndrome protein family , shortened first member of the WASP proteins , or protein WAVE1 called, is a regulatory protein that the gene WASF1 is coded. Together with other members of the WASP / WAVE proteins, it plays an important role in regulating the actin cytoskeleton by regulating the Arp 2/3 complex in particular .

Individual evidence

  1. UniProt Q92558