Y-chromosomal inheritance

The Y-chromosomal inheritance , also called Holandrian inheritance (from ancient Greek ὅλος holos 'whole' and ἀνδρός andros 'man'), is a gonosomal inheritance . It is one of the monogenic inheritance patterns that follow Mendel's rules .

The gene that determines the trait is on the Y chromosome . With this inheritance, the characteristics are only expressed in men, which means that a man with characteristics can only have sons with characteristics (inheritance in the paternal line). In humans, in contrast to the X-linked inheritance , no hereditary diseases are known in the Holandrian inheritance. So far, only male sex determination has been proven with certainty as a Y-chromosomal feature.

From 1907 to the 21st century it was assumed that excessive hair growth ( hypertrichosis ) in the external auditory canal ( hypertrichosis pinnae auris ) is inherited in a Y-chromosomal manner. However, this inheritance is now being questioned.

further reading

• KR Dronamraju: Y-linkage in man. In: Nature . Volume 201, January 1964, pp. 424-425, ISSN  0028-0836 . PMID 14110028 .

Individual evidence

1. ↑ salerno: Page no longer available , search in web archives: inheritance.
2. ↑ C. Tommasi: Ipertricosi auricolare famigliare. In: Arch Psichiatr Neuropat Antropol Crim Med Legale. Volume 28, 1907, pp. 60-67.
3. ↑ Hairy Ears.  In: Online Mendelian Inheritance in Man . (English)
4. ^ Hairy Ears, Y-linked.  In: Online Mendelian Inheritance in Man . (English)
5. ↑ C. Stern, WR Wall Center, SS Sarkar: New data on the problem-of y-linkage of hairy pinnae. In: American Journal of Human Genetics . Volume 16, December 1964, pp. 455-471, ISSN  0002-9297 . PMID 14250426 . PMC 1932324 (free full text).
6. ↑ AC Lee, A. Kamalam et al. a .: Molecular evidence for the absence of Y-linkage of the Hairy Ears trait. In: European journal of human genetics . Volume 12, Number 12, December 2004, pp. 1077-1079, ISSN  1018-4813 . doi : 10.1038 / sj.ejhg.5201271 . PMID 15367914 .