Yellow nail syndrome
| Classification according to ICD-10 | |
|---|---|
| L60.5 | Yellow nail syndrome [Yellow nail syndrome] |
| ICD-10 online (WHO version 2019) | |
The yellow nail syndrome (YNS) is a syndrome of unclear origin, in which the nails thicken and yellowish discoloration as a result of growth disorders and furthermore fluid accumulations in the chest and lymphedema develop. In addition, dilated bronchi and recurrent sinus infections can occur .
Epidemiology
YNS is a rare disease (1: 500,000 to 1: 1,000,000). Women are affected a little more often. Usually it is an independent disease without an underlying disease; sometimes also in the context of cancer ( paraneoplasia ) or immunological , rheumatological , endocrinological diseases, kidney diseases or tuberculosis .
Pathophysiology
The development of pleural effusions is the result of impaired lymphatic drainage or possibly also a loss of protein. Slower nail growth leads to thickening and yellowing of the nails.
therapy
In the case of extensive pleural effusions, a relieving puncture is necessary. Rapidly running effusions require the lung membrane to be glued together ( pleurodesis ). The nail changes can regress with treatable underlying disease. Local or systemic therapy with vitamin E is recommended.
literature
- M. Riedel: Multiple Effusions and Lymphedema in the Yellow Nail Syndrome. In: Circulation. 105, 2002, p. E25.
- M. Riedel, V. Bohanes: The Yellow Nail Syndrome. ( Memento of September 30, 2007 in the Internet Archive ) In: Pneumology. 57, 2003, pp. 144-148.
- H. Alkadhi et al: Yellow Nail Syndrome. In: Respiration. 72, 2005, p. 197.
- H. Klee: Pneumological Case Reports - Yellow Nail Syndrome 2007.
Web links
- Photographs of the typical changes on the fingernails ( Memento from September 29, 2007 in the Internet Archive )
