Haemophilus parainfluenzae: Difference between revisions
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==Natural genetic transformation== |
==Natural genetic transformation== |
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''H. parainfluenzae'' biotypes I and II are capable of [[transformation (genetics)|natural genetic transformation]].<ref name="pmid9662612">{{cite journal |vauthors=Gromkova RC, Mottalini TC, Dove MG |title=Genetic transformation in Haemophilus parainfluenzae clinical isolates |journal=Curr. Microbiol. |volume=37 |issue=2 |pages=123–6 |year=1998 |pmid=9662612 }}</ref> Natural genetic transformation is a bacterial adaptation for [[DNA]] transfer. In order for a bacterium to bind, take up and recombine exogenous DNA into its [[genome]] it must enter a special physiological state termed [[natural competence]]. In ''H. parainfluenzae'', competence is induced during the [[bacterial growth|late stationary phase of growth]].<ref name="pmid9662612" /> Natural DNA transformation may play a major role in the exchange of genetic information among ''H. parainfluenzae'' isolates. Acute H. parainfluenzae infections must be treated with antibiotics. Beta-lactam agents such as amoxicillin and ampicillin are antibiotics that are effective against H. parainfluenzae. The Duration of Antibiotic Therapy depends on the severity of the infection. In 40% of infective endocarditis cases caused by H. parainfluenzae, the best treatment is a valve replacement. |
''H. parainfluenzae'' biotypes I and II are capable of [[transformation (genetics)|natural genetic transformation]].<ref name="pmid9662612">{{cite journal |vauthors=Gromkova RC, Mottalini TC, Dove MG |title=Genetic transformation in Haemophilus parainfluenzae clinical isolates |journal=Curr. Microbiol. |volume=37 |issue=2 |pages=123–6 |year=1998 |pmid=9662612 }}</ref> Natural genetic transformation is a bacterial adaptation for [[DNA]] transfer. In order for a bacterium to bind, take up and recombine exogenous DNA into its [[genome]] it must enter a special physiological state termed [[natural competence]]. In ''H. parainfluenzae'', competence is induced during the [[bacterial growth|late stationary phase of growth]].<ref name="pmid9662612" /> Natural DNA transformation may play a major role in the exchange of genetic information among ''H. parainfluenzae'' isolates. |
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==Treatment== |
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Acute H. parainfluenzae infections must be treated with antibiotics. Beta-lactam agents such as amoxicillin and ampicillin are antibiotics that are effective against H. parainfluenzae. The Duration of Antibiotic Therapy depends on the severity of the infection. In 40% of infective endocarditis cases caused by H. parainfluenzae, the best treatment is a valve replacement.<ref>[https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/haemophilus-parainfluenzae.html Canada, P. H. A. of. (2020, December 21). Government of Canada. Canada.ca]</ref> |
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==References== |
==References== |
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{{Reflist}} |
{{Reflist}} |
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https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/haemophilus-parainfluenzae.html Canada, P. H. A. of. (2020, December 21). Government of Canada. Canada.ca. |
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==External links== |
==External links== |
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Revision as of 20:54, 19 March 2023
| Haemophilus parainfluenzae | |
|---|---|
Scientific classification 
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| Domain: | Bacteria |
| Phylum: | Pseudomonadota |
| Class: | Gammaproteobacteria |
| Order: | Pasteurellales |
| Family: | Pasteurellaceae |
| Genus: | Haemophilus |
| Species: | H. parainfluenzae
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| Binomial name | |
| Haemophilus parainfluenzae Rivers 1922 (Approved Lists 1980)[1]
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Haemophilus parainfluenzae is a species of Haemophilus.
It is one of the HACEK organisms.[2] H. parainfluenzae is an opportunistic pathogen that has been associated with endocarditis, bronchitis, otitis, conjunctivitis, pneumonia, abscesses and genital tract infections.
Natural genetic transformation
H. parainfluenzae biotypes I and II are capable of natural genetic transformation.[3] Natural genetic transformation is a bacterial adaptation for DNA transfer. In order for a bacterium to bind, take up and recombine exogenous DNA into its genome it must enter a special physiological state termed natural competence. In H. parainfluenzae, competence is induced during the late stationary phase of growth.[3] Natural DNA transformation may play a major role in the exchange of genetic information among H. parainfluenzae isolates.
Treatment
Acute H. parainfluenzae infections must be treated with antibiotics. Beta-lactam agents such as amoxicillin and ampicillin are antibiotics that are effective against H. parainfluenzae. The Duration of Antibiotic Therapy depends on the severity of the infection. In 40% of infective endocarditis cases caused by H. parainfluenzae, the best treatment is a valve replacement.[4]
References
- ^ "Species: Haemophilus parainfluenzae". lpsn.dsmz.de.
- ^ HACEK Group Infections at eMedicine
- ^ a b Gromkova RC, Mottalini TC, Dove MG (1998). "Genetic transformation in Haemophilus parainfluenzae clinical isolates". Curr. Microbiol. 37 (2): 123–6. PMID 9662612.
- ^ Canada, P. H. A. of. (2020, December 21). Government of Canada. Canada.ca
External links
- "Haemophilus parainfluenzae". NCBI Taxonomy Browser. 729.
- Type strain of Haemophilus parainfluenzae at BacDive - the Bacterial Diversity Metadatabase
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