Tolperisone: Difference between revisions

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[[Category:Piperidines]]
[[Category:Piperidines]]
[[Category:Muscle relaxants]]

Revision as of 15:45, 27 May 2008

Tolperisone
Clinical data
ATC code
Identifiers
  • 2-methyl-1-(4-methylphenyl)-3-(1-piperidyl)propan-1-one
CAS Number
PubChem CID
CompTox Dashboard (EPA)
ECHA InfoCard100.010.889 Edit this at Wikidata
Chemical and physical data
FormulaC16H23NO
Molar mass245.36 g/mol g·mol−1
3D model (JSmol)
  • C1CCCN(C1)CC(C(C2=CC=C(C=C2)C)=O)C

Tolperisone, a piperidine derivative, is a centrally acting muscle relaxant. Brand names include Mydocalm and Mydeton.

External links

  • Hofer D, Lohberger B, Steinecker B, Schmidt K, Quasthoff S, Schreibmayer W (2006). "A comparative study of the action of tolperisone on seven different voltage dependent sodium channel isoforms". Eur J Pharmacol. 538 (1–3): 5–14. PMID 16650844.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  • Kocsis P, Farkas S, Fodor L, Bielik N, Thán M, Kolok S, Gere A, Csejtei M, Tarnawa I (2005). "Tolperisone-type drugs inhibit spinal reflexes via blockade of voltage-gated sodium and calcium channels". J Pharmacol Exp Ther. 315 (3): 1237–46. PMID 16126840.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  • Ribi C, Vermeulen C, Hauser C (2003). "Anaphylactic reactions to tolperisone (Mydocalm)". Swiss Med Wkly. 133 (25–26): 369–71. PMID 12947534.{{cite journal}}: CS1 maint: multiple names: authors list (link)