Toxoflavin

Toxoflavin^[1]^[2]
Names
	IUPAC name 1,6-Dimethylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione
	Other names Toxoflavine; Xanthothricin; Xanthotricin
Identifiers
CAS Number	84-82-2 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:80729;
ChEMBL	ChEMBL578512 ;
ChemSpider	59912 ;
ECHA InfoCard	100.213.079
PubChem CID	66541;
UNII	5N5YI4IP1P ;
	InChI InChI=1S/C7H7N5O2/c1-11-6(13)4-5(10-7(11)14)12(2)9-3-8-4/h3H,1-2H3 Key: SLGRAIAQIAUZAQ-UHFFFAOYSA-N ; InChI=1S/C7H7N5O2/c1-11-6(13)4-5(10-7(11)14)12(2)9-3-8-4/h3H,1-2H3;
	SMILES O=C2\N=C1C(=N/C=N\N1C)\C(=O)N2C;
Properties
Chemical formula	C7H7N5O2
Molar mass	193.166 g·mol−1
Appearance	Bright yellow solid
Melting point	172 to 173 °C (342 to 343 °F; 445 to 446 K) (decomposes)
Hazards
	Lethal dose or concentration (LD, LC):
LD50 (median dose)	1.7 mg/kg (IV, mouse); 8.4 mg/kg (oral, mouse)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Toxoflavin is a toxin produced by a variety of bacteria including Burkholderia gladioli. It also has antibiotic properties.^[3]

Toxoflavin acts as a pH indicator, changing between yellow and colorless at pH 10.5.^[1]

References[edit]

^ ^a ^b Merck Index, 11th Edition, 9480
^ Toxoflavin, at the Comparative Toxicogenomics Database
^ Machlowitz, Roy A.; Fisher, W. P.; McKay, Betsey S.; Tytell, Alfred A.; Charney, Jesse (1954). "Xanthothricin, a new antibiotic". Antibiotics & Chemotherapy (Northfield, Ill.). Antibiotics and Chemotherapy. 4 (3): 259–261. PMID 24542943.

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