1,2-dihydropyridine
Structural formula | ||||||||||
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General | ||||||||||
Surname | 1,2-dihydropyridine | |||||||||
other names |
Dihydropyridine |
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Molecular formula | C 5 H 7 N | |||||||||
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properties | ||||||||||
Molar mass | 81.12 g mol −1 | |||||||||
safety instructions | ||||||||||
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As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . |
1,2-Dihydropyridine is a chemical compound consisting of a six-membered unsaturated ring with one nitrogen atom. Its unsaturated analogue is pyridine . 1,2-dihydropyridine is an isomer to 1,4-dihydropyridine .
presentation
The reduction of pyridine using lithium aluminum hydride gives a mixture of 1,2-dihydropyridine, 1,4-dihydropyridine and 2,5-dihydropyridine .
Biological importance
Among the 1,2-dihydropyridine derivatives, the AMPA antagonist perampanel , which is used as an anticonvulsant in epilepsy , is of biological importance .
Individual evidence
- ↑ This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
- ↑ DD Tanner, Yang, C.-M .: On the structure and mechanism of formation of the Lansbury reagent, lithium tetrakis (N-dihydropyridyl) aluminate , in J. Org. Chem. , 1993 , 58 , 1840-1846 doi : 10.1021 / jo00059a041 .
- ^ DM Stout, AI Meyers: Recent advances in the chemistry of dihydropyridines , in Chem. Rev. , 1982 , 82 , 223-243 doi : 10.1021 / cr00048a004 .