Acrocyanosis

from Wikipedia, the free encyclopedia
Classification according to ICD-10
I73.8 Other specified peripheral vascular diseases
acrocyanosis
ICD-10 online (WHO version 2019)

Under acrocyanosis (also: Akroasphyxie , Acroasphyxia or acrocyanosis ) refers to a blue coloration ( cyanosis ) of the appendages ( extremities ), such as the fingers , toes , nose and ears , which occurs predominantly in young women. Other characteristics are cold and damp skin, possibly doughy swelling and paresthesia . If the discoloration is pushed away, it reappears when you let go of the periphery . This is known as the iris phenomenon .

A chronic form is also called Cassirer syndrome or Cassirer-Crocq syndrome ( Latin : Acroasphyxia chronica hypertrophica ) after the German neurologist Richard Cassirer .

root cause

Temperatures between 15 ° C and 18 ° C trigger acrocyanosis. Acrocyanosis is also a symptom of heart and lung diseases (e.g. Eisenmenger's reaction ) and of cryoglobulinemia and anorexia nervosa .

Pathogenesis

Due to the influence of low temperatures, the arterioles in the acres contract more than normal, which leads to an undersupply of oxygen-rich blood . The symptoms were therefore also referred to as vasoneurotic acrocyanosis . The predominance of oxygen-poor blood causes the fingers and toes to turn blue. Cold agglutinins also react with the red blood cells when it is cold and lead to reversible clumping, which can then temporarily clog the smaller blood vessels .


Individual evidence

  1. ^ R. Cassirer: The vasomotor trophic neuroses. Berlin, Karger. 1901. 2nd edition, 1912
  2. Who named it
  3. ^ H. Schubothe: Internal diseases caused by physical environmental factors. In: Ludwig Heilmeyer (ed.): Textbook of internal medicine. Springer-Verlag, Berlin / Göttingen / Heidelberg 1955; 2nd edition, ibid. 1961, pp. 1161-1194, here: p. 1165 ( attacks of vasoneurotic acrocyanosis ).