Analeptic
Analeptics are substances that are administered in therapeutic amounts and have a stimulating effect on the nervous system or individual functional areas, such as the respiratory center . In higher doses , they are poisonous and cause cramps . Their therapeutic range is narrow.
Active ingredients
- Almitrine
- Amiphenazole
- Bemegrid
- Caffeine
- Dimeflin
- Doxapram
- Camphor (camphor)
- Etamivan
- Lobeline
- Mepixanox
- Methylphenidate
- Nikethamide
- nicotine
- Pentetrazole
- Prethcamid
- Strychnine
application areas
- Caffeine, as caffeine citrate , in gynecology for stimulating the respiration in respiratory arrest preterm infants.
- Doxapram:
- if drug-induced respiratory depression (i.e. decreased respiratory drive ) persists after anesthesia .
- if opioids trigger respiratory depression as a side effect and the pain-relieving effect of these active substances is to be retained.
- in chronic lung diseases with hypercapnia .
literature
- Simon Young, Ryan Campbell: Central nervous system stimulants: basic pharmacology and relevance to anesthesia and critical care . In: Anesthesia & Intensive Care Medicine . 16, No. 1, 2015, pp. 21-25. doi : 10.1016 / j.mpaic.2014.10.005 .
- PM Wax: Analeptic use in clinical toxicology: A historical appraisal . In: Journal of Toxicology Clinical Toxicology . 35, No. 2, 1997, pp. 203-209. doi : 10.3109 / 15563659709001195 . PMID 9120893 .
