Nikethamide
Structural formula | ||||||||||||||||
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General | ||||||||||||||||
Non-proprietary name | Nikethamide | |||||||||||||||
other names |
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Molecular formula | C 10 H 14 N 2 O | |||||||||||||||
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Drug information | ||||||||||||||||
ATC code | ||||||||||||||||
Drug class |
stimulant |
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properties | ||||||||||||||||
Molar mass | 178.23 g mol −1 | |||||||||||||||
Physical state |
solid to liquid |
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density |
1.06 g cm −3 (25 ° C) |
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Melting point |
23 ° C |
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boiling point |
296-300 ° C |
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Refractive index |
1.524 (20 ° C) |
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safety instructions | ||||||||||||||||
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As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions . Refractive index: Na-D line , 20 ° C |
Nikethamid or Nicethamid is a psychostimulant and essentially causes breathing and circulatory stimulation . In the past, it was used as an emergency medical countermeasure after overdoses of sedatives or sleeping pills such as veronal (Nikethamid was known under its trade name Coramin ).
In sport, like all stimulants, nikethamide is a prohibited doping agent . The case of the American sprint world champion Torri Edwards became known , who was convicted of taking nikethamide in 2004 and was therefore banned for two years.
In 2012, the 12-year-old Polish kart athlete Igor Walilko was acquitted by the International Sports Court after a doping control had previously found elevated nikethamide levels and a two-year ban had been issued. The sports court judged the ban as excessive and disproportionate. The boy previously ate energy bars that contained nikethamide.
As part of the 2013 BMW Open was Marin Cilic tested at a doping test positive for nikethamide. Čilić stated that he unknowingly ingested the drug via a tablet obtained from a pharmacy. As this was not intended to increase performance, he received a reduced suspension of nine months, which was retroactive from May 1, 2013 to January 31, 2014. The International Court of Sports then reduced the suspension to only four months, as it did not consider Čilić's guilt as serious as the ITF arbitration tribunal .
In Switzerland, lozenges are sold to combat fatigue and contain glucose and nicethamide.
Individual evidence
- ↑ a b c d e f data sheet N, N-Diethylnicotinamide from Sigma-Aldrich , accessed on April 16, 2011 ( PDF ).
- ↑ Hans Killian : There is only God behind us. Sub umbra dei. A surgeon remembers. Kindler, Munich 1957; here: Licensed edition as Herder paperback (= Herder library. Volume 279). Herder, Freiburg / Basel / Vienna 1975, ISBN 3-451-01779-2 , pp. 29 f., 35 and 192.
- ↑ James Corrigan: The Last Word: War on drugs guilty of wounding youngsters .
- ↑ Doping case: Was Cilic tested positive? , tennisnet.com. Retrieved July 30, 2013.
- ^ Decision In The Case Of Marin Cilic , atpworldtour.com. Retrieved September 16, 2013.
- ↑ CAS reduces doping ban for Cilic to four months , tennisnet.com. Retrieved October 26, 2013.