Parinaud syndrome

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Classification according to ICD-10
H49.8 Parinaud's Syndrome - [Ophthalmoplegia]
ICD-10 online (WHO version 2019)

Under the Parinaud syndrome is defined as the occurrence of vertical gaze palsy and other neurological deficits by damage to the cranial nerve nuclei in the region of the midbrain. In addition, there is a lack of convergence reaction of the eyes, nystagmus and dilated pupil ( mydriasis ) in the absence of a pupillary reflex . Due to the vertical paralysis of the eye, the affected eye cannot carry out any follow -up or command movements upwards, and much less often downwards. In terms of reflection, however, this is possible ( doll's head phenomenon ).

The cause is damage to the supplying cranial nerves or their nuclei in the area of ​​the dorsal midbrain (four-hill plate, pretectal region) due to aqueduct stenosis , a brain tumor ( pinealoma ), multiple sclerosis , encephalitis or cerebral infarction after a circulatory disorder. In small children and newborns, Parinaud's syndrome is a characteristic sign of an increase in intracranial pressure with the accompanying sunset phenomenon . Since damage on both sides usually occurs, both eyes are also affected. Treatment depends on the underlying disease.

Others

Parinaud's syndrome should not be confused with Parinaud's disease , an infection with the bacterium Francisella tularensis . As Okuloglanduläres syndrome Parinaud the occurrence of a one-sided is conjunctivitis associated with lymph node swelling in front of the ear and under the jaw called. It occurs not only in Parinaud's disease, but also in syphilis , tuberculosis, and fungal infections .

See also

swell

  1. ^ Matthias Sachsenweger: Ophthalmology (= dual series ). 2nd, completely revised and expanded edition. Thieme, Stuttgart et al. 2003, ISBN 3-13-128312-2 , p. 90: Parinaud conjunctivitis.