Arthur Brockhaus

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Hans-Arthur Brockhaus (born April 9, 1927 ) is a German chemist in the field of environmental medicine.

Brockhaus has a doctorate in chemistry. In the 1960s he developed a drug for the treatment of silicosis , PVNO (poly-2-vinylpyridine-N-oxide) at the Institute for Air Hygiene and Silicosis Research in Düsseldorf in collaboration with Hans-Werner Schlipköter . The polymer protects the macrophages from the quartz grains and thus prevents necrosis . It not only has a preventive effect, but also leads to regression of pulmonary fibrosis that has already occurred in animal experiments . The preventive effect against pulmonary fibrosis is limited, as later showed, to pure quartz dust.

He stayed with Schlipköter at the Institute for Environmental Hygiene at the University of Düsseldorf and later examined, among other things, lead exposure and exposure to other heavy metals in the population. He was involved in a European multinational study of the effects of lead exposure on children in terms of effects on the nervous system and brain in the 1980s.

In 1968 he received the Robert Koch Prize with Schlipköter .

literature

  • Gesellschaft Deutscher Chemiker: Nachrichten aus Chemie, Technik und Laboratorium, Volume 35, Page 292, Verlag Chemie., 1987

Individual evidence

  1. ↑ Also P 204. Brockhaus, Schlipköter animal experiments on the effect of quartz dust in the presence of basic and acidic ion exchangers , contributions to silicosis research 1960, special volume basic questions of silicosis research, p. 155, the same The inhibition of experimental silicosis by subcutaneous administration of polyvinyl-N-oxide , Klinische Wochenschrift, Volume 39, 1961, pp. 1182-9, Brockhaus, Schlipköter, Dolgner A contribution to the therapy of experimental silicosis , German Medical Wochenschrift, Volume, 88, 1963, p. 1895, Brockhaus, Schlipköter, F. Pott Tiermedizinische Basics of medical silicosis prophylaxis with polyvinylpyridine-N-oxide (P 204) , Deutsche Medizinische Wochenschrift, Volume 93, 1968, pp. 2479-2482.
  2. ↑ It has no preventive effect on mine dust. Joos u. a. Silicosis report, Volume 16, 1987, p. 223, see also Gabriele Isensee Morphometric examinations of rat lungs after exposure to quartz with and without PVNO treatment , dissertation, University of Düsseldorf 2000, pdf , p. 5.
  3. ↑ Spiegel August 28, 1989, wash your hands , too high levels of lead in Braubach near Lahnstein due to the lead and silver smelter of the Deutsche Metallgesellschaft located there.
  4. ↑ Gerhard Winneke et al. a. Results from the European multicenter study on lead neurotoxicity in children: Implications for risk assessment , Neurotoxicology and Teratology , Volume 12, 1990, p. 533, doi : 10.1016 / 0892-0362 (90) 90022-5 .
  5. ↑ Westermanns monthly notebooks 1968.
personal data
SURNAME Brockhaus, Arthur
ALTERNATIVE NAMES Brockhaus, Hans-Arthur
BRIEF DESCRIPTION German chemist
DATE OF BIRTH April 9, 1927