Bactoprenol

from Wikipedia, the free encyclopedia
Structural formula
Structural formula of bactoprenol
General
Surname Bactoprenol
Molecular formula C 55 H 92 O
External identifiers / databases
CAS number 12777-41-2
PubChem 6449977
ChemSpider 4952635
Wikidata Q409695
properties
Molar mass 769.32 g mol −1
safety instructions
GHS hazard labeling
no classification available
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Bactoprenol (undecaprenol) in the form of its diphosphate is a lipid carrier (C 50 to C 60 isoprenoid alcohol) that is bound to the cytoplasmic membrane of bacteria .

Its function is that the sugar intermediates are made sufficiently hydrophobic during the synthesis of peptidoglycan so that they can be channeled through the cytoplasmic membrane ("flipping"). Characterized that is disaccharide - pentapeptide transported in the peptidoglycan network to the outside, where the installation takes place. The lipid carrier jumps back into the cytoplasm and takes up a disaccharide pentapeptide again.

This passage of sugar intermediates can also be inhibited by antibiotics such as bacitracin , which can be produced by some species of Bacillus.

Individual evidence

  1. This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
  2. ^ Peter Nuhn: Naturstoffchemie , S. Hirzel Verlag Stuttgart, 2nd edition, 1990, p. 232, ISBN 3-7776-0473-9 .