Bretylium

Structural formula
Counterion not shown
General
Surname	Bretylium
other names	(2-bromophenyl) methyl-ethyl-dimethyl-ammonium (2-bromobenzyl) ethyldimethylammonium p -toluenesulfonate ( tosylate )
Molecular formula	C 11 H 17 BrN + C 18 H 24 BrNO 3 S (tosylate)
External identifiers / databases
CAS number 59-41-6 61-75-6 (tosylate) PubChem 2431 DrugBank DB01158 Wikidata Q420026
Drug information
ATC code	C01 BD02
properties
Molar mass	413.5 g mol −1 414.36 g mol −1 (tosylate)
Physical state	firmly
safety instructions
Please note the exemption from the labeling requirement for drugs, medical devices, cosmetics, food and animal feed GHS labeling of hazardous substances Tosylate Caution H and P phrases H: 302-312-332 P: 261-280-301 + 312 + 330
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Bretylium is a Vaughn-Williams class III ( potassium channel blocker ) antiarrhythmic that is not approved in Germany . It is used primarily in the USA, where it is marketed under the trade name Bretylol®, in the treatment of ventricular tachycardias and ventricular fibrillation . Most specialist societies no longer recommend the use of Bretylium, as its superiority over other drugs that are approved for the same indication (e.g. lidocaine ) is questionable and the administration of Bretylium in many cases results in a drop in blood pressure that is very difficult to control .

Individual proof

1. ↑ ^{a b} Data sheet Bretylium tosylate, United States Pharmacopeia (USP) Reference Standard from Sigma-Aldrich , accessed on November 1, 2016 ( PDF ).

This article is about a health issue. It is not used for self-diagnosis and does not replace a diagnosis by a doctor. Please note the information on health issues !