CCL13
CCL13 | ||
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other names |
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Properties of human protein | ||
Mass / length primary structure | 98 amino acids, 10986 Da | |
Identifier | ||
External IDs | ||
Orthologue | ||
human | House mouse | |
Entrez | 6357 | 20296 |
UniProt | Q99616 | P10148 |
PubMed search | 6357 |
20296
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CCL13 ( English CC chemokine ligand 13 ) is a cytokine belonging to the family of the C-C chemokines .
properties
CCL8 is involved in inflammatory processes. It is chemotactic for and activates various immune cells including monocytes , eosinophils , T lymphocytes and basophils by binding to CCR2 , CCR3 and CCR5 . CCL13 is involved in the development of asthma . CCL13 is induced by the cytokines interleukin-1 and TNF-α .
Individual evidence
- ↑ Blanpain et al., CCR5 binds multiple CC chemokines: MCP-3 acts as a natural antagonist. Blood. 1999, 94: 1899-905.
- ↑ Lamkhioued et al., Monocyte chemoattractant protein (MCP) -4 expression in the airways of patients with asthma. Induction in epithelial cells and mononuclear cells by proinflammatory cytokines. Am J Respir Crit Care Med. 2000, 162: 723-32.