COL28A1
| Collagen type XXVIII, alpha 1 | ||
|---|---|---|
| other names |
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| Properties of human protein | ||
| Mass / length primary structure | 1,125 amino acids , 116,657 Da | |
| Isoforms | 3 | |
| Identifier | ||
| Gene name | COL28A1 | |
| External IDs | ||
| Occurrence | ||
| Parent taxon | Bilateria | |
| Orthologue | ||
| human | House mouse | |
| Entrez | 340267 | 213945 |
| Ensemble | ENSG00000215018 | ENSMUSG00000068794 |
| UniProt | Q2UY11 | Q2UY11 |
| Refseq (mRNA) | NM_001037763 | NM_001037865 |
| Refseq (protein) | NP_001032852.2 | NP_001032954.1 |
| Gene locus | Chr 7: 7.36 - 7.54 Mb | Chr 6: 8 - 8.19 Mb |
| PubMed search | 340267 |
213945
|
Collagen type XXVIII, alpha 1 is a collagen that the gene COL28A1 is encoded. It forms homotrimers , which in turn form collagen fibrils of type XXVIII.
properties
Type XXVIII collagen contains the Von Willebrand factor type A domain. Collagen XXVIII is mainly located in the sciatic nerve and on the basement membrane of some Schwann cells . It is also an integral part of the Ranvier lace ring and surrounds non- myelinated glial cells .
Web links
Individual evidence
- ↑ Guido Veit, Birgit Kobbe, Douglas R. Keene, Mats Paulsson, Manuel Koch, Raimund Wagener: Collagen XXVIII, a novel by Willebrand factor A domain-containing protein with many imperfections in the collagenous domain . In: J Biol Chem . 281, No. 6, February 10, 2006, pp. 3494-3504. doi : 10.1074 / jbc.M509333200 . PMID 16330543 .
- ↑ Sophie Grimal, Sylvie Puech, Raimund Wagener, Stéphanie Ventéo, Patrick Carroll, Agnès Fichard-Carroll: Collagen XXVIII is a distinctive component of the peripheral nervous system nodes of ranvier and surrounds nonmyelinating glial cells . In: Glia . 58, No. 16, December 2010, pp. 1977-2987. doi : 10.1002 / glia.21066 . PMID 20830809 .