Charlotte Esser

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Charlotte Esser is a biologist, immunologist and adjunct professor at the Leibniz Institute for Environmental Medicine Research at the University of Düsseldorf . Her main area of ​​research is the aryl hydrocarbon receptor (AhR) in immunotoxicology , with a particular focus on the physiological role of this transcription factor . She deals with the effects of environmental chemicals or nutritional supplements on the immune functions of the intestines and skin.

Career

Charlotte Esser studied biology from 1977 to 1985 with a focus on zoology , genetics and biochemistry at the universities in Cologne and Tübingen and at Duke University in the USA. She did her doctorate in 1990 with Andreas Radbruch in the field of immunology at the Institute for Genetics of the University of Cologne with a thesis on the molecular control of immunoglobulin class changes . After a three-year postdoc at the Medical Institute for Environmental Hygiene at the University of Düsseldorf, she began research semesters at the Basel Institute for Immunology in 1993 and at the INRA in Toulouse in 1995 , before returning to her Düsseldorf institute as deputy head of department until 2001.

1998 habilitation they are at the Düsseldorf University with a thesis on the effects of certain external pathogens to immune cells. After a sabbatical in the laboratory of the pathologist Abul K. Abbas at Harvard and at the University of California in San Francisco , she became group leader of the Leibniz Institute for Environmental Medicine Research in 2001 . In 2004 she was appointed adjunct professor at the mathematics and natural science faculty in Düsseldorf.

In addition to her working group, she headed, among other things, the graduate college "Food ingredients as signal generators in the intestine". The German Society for Toxicology honored Esser with its GT Toxicology Prize in 2009.

Charlotte Esser is a member of various specialist societies, among other things she was the spokesperson for the working group immunotoxicology in the German Society for Experimental and Clinical Pharmacology and Toxicology . She is also committed to equality - among other things, she is the spokesperson for the commission for equality and career advancement in the German Society for Immunology , mentor at the University of Düsseldorf.

Charlotte Esser is the daughter of the artist Georg Esser .

Publications (selection)

  • Transcription of recombinogenic sequences from the mouse IgH locus. (Dissertation). Cologne 1990.
  • Effects of aryl hydrocarbon receptor binding exogenous noxae on the development and functionality of thymocytes and T cells . (Habilitation thesis). Düsseldorf 1996.
  • The immune phenotype of AhR null mouse mutants: Not a simple mirror of xenobiotic receptor over-activation . In: Biochemical Pharmacology . tape 77 , no. 4 , February 2009, ISSN  0006-2952 , p. 597-607 , doi : 10.1016 / j.bcp.2008.10.002 .
  • with Bettina Jux, Stephanie Kadow: Langerhans Cell Maturation and Contact Hypersensitivity Are Impaired in Aryl Hydrocarbon Receptor-Null Mice . In: The Journal of Immunology . tape 182 , no. 11 , May 19, 2009, ISSN  0022-1767 , p. 6709-6717 , doi : 10.4049 / jimmunol.0713344 .
  • with Susanne Stutte, Bettina Jux, Irmgard Förster: CD24a Expression Levels Discriminate Langerhans Cells from Dermal Dendritic Cells in Murine Skin and Lymph Nodes . In: Journal of Investigative Dermatology . tape 128 , no. 6 , June 2008, ISSN  0022-202X , p. 1470-1475 , doi : 10.1038 / sj.jid.5701228 .
  • with Annette Esser: Georg Esser - Life and Work . Self-published, Cologne and Bad Kreuznach 2018, ISBN 978-3-00-058818-1 .

Web links

Individual evidence

  1. ^ Esser group: Role of the AhR in immunotoxicology - IUF. Retrieved March 23, 2020 .
  2. ↑ a b 2009 GT Toxicology Prize. Retrieved March 24, 2020 .
  3. ↑ a b Curriculum Vitae Charlotte Esser. In: iuf-duesseldorf.de. Retrieved March 24, 2020 .
  4. ↑ Transcription of recombinogenic sequences of the mouse IgH locus. Cologne 1990.
  5. ↑ a b c d CV Charlotte Esser. In: dgpt-online.de. 2009, accessed March 24, 2020 .
  6. ↑ Prof. Dr. Charlotte Esser - AcademiaNet. Retrieved March 24, 2020 .
  7. ↑ Effects of aryl hydrocarbon receptor binding exogenous noxae on the development and functionality of thymocytes and T cells . (Habilitation thesis). Düsseldorf 1996.
  8. ↑ dgpt-online.de: working groups and working groups. Retrieved March 24, 2020 .
personal data
SURNAME Esser, Charlotte
BRIEF DESCRIPTION Biologist and immunologist
DATE OF BIRTH 20th century