Choline transporter-like protein 1
Choline transporter-like protein 1 | ||
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other names |
CDw92, Solute carrier family 44 member 1, CD92, SLC441 |
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Properties of human protein | ||
Mass / length primary structure | 657 amino acids , 73,302 Da | |
Identifier | ||
External IDs | ||
Orthologue (human) | ||
Entrez | 23446 | |
Ensemble | ENSG00000070214 | |
UniProt | Q8WWI5 | |
Refseq (mRNA) | NM_001286730.1 | |
Refseq (protein) | NP_001273659.1 | |
PubMed search |
23446
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Choline transporter-like protein 1 (synonym CD92 ) is a surface protein from the group of transport proteins .
properties
CD92 is produced in various hematopoietic cells. It transports choline through the cell membrane and is thus indirectly involved in the biosynthesis of choline-containing phospholipids . CD92 is phosphorylated and myristylated . It probably binds nectin-like 4 .
Web links
Individual evidence
- ^ Z. Yuan, A. Tie, M. Tarnopolsky, M. Bakovic: Genomic organization, promoter activity, and expression of the human choline transporter-like protein 1. In: Physiological genomics. Volume 26, Number 1, June 2006, pp. 76-90, doi : 10.1152 / physiolgenomics.00107.2005 , PMID 16609143 .
- ↑ C. Heffernan, MR Jain, T. Liu, H. Kim, K. Barretto, H. Li, P. Maurel: Nectin-like 4 Complexes with Choline Transporter-like Protein-1 and Regulates Schwann Cell Choline Homeostasis and Lipid Biogenesis in vitro. In: The Journal of biological chemistry. Volume 292, Number 11, March 2017, pp. 4484-4498, doi : 10.1074 / jbc.M116.747816 , PMID 28119456 , PMC 5377767 (free full text).