Christian Kurts

Christian Kurts (born November 27, 1964 in Helmstedt ) is a German university professor, immunologist and nephrologist .

Life and accomplishments

Christian Kurts studied medicine and physics at the University of Göttingen from 1985 to 1991 . There he received his doctorate in medicine in 1991 . From November 1991 to March 1995 and from May 1998 to September 2000 he worked as an assistant doctor and research assistant in internal medicine and nephrology at the Hannover Medical School . From April 1995 to March 1998 he spent a three-year research stay at the Walter and Eliza Hall Institute for Medical Research (WEHI) in Melbourne , Australia with Jacques Miller , where he researched antigen cross-presentation and autoimmunity . From October 2000 to March 2003, as head of a junior research group for the state of North Rhine-Westphalia at the Aachen University Hospital, he carried out fundamental research on dendritic cells in the kidney and completed further training in the field of nephrology in internal medicine . In 2002 he was a visiting researcher at the La Jolla Institute for Allergy and Immunology (LIAI), San Diego , USA . In 2003 Kurts was appointed to a professorship for molecular immunology at the University Clinic Bonn of the Rheinische Friedrich-Wilhelms-Universität Bonn and six years later director at the institutes for molecular medicine and experimental immunology there. He deals scientifically with the cell biology and dynamics of cross-presentation, immune tolerance and the function of dendritic cells in various organs, especially the urogenital tract.

Awards

1986: Scholarship from the German National Academic Foundation
1992: PhD award from the German Society for Nephrology
1999: Hans Adolf Krebs Prize for basic medical research
2001: Heisenberg grant from the German Research Foundation
2010: Hans-U.-Zollinger-Award of the German Society for Nephrology
2012: Gottfried Wilhelm Leibniz Prize of the German Research Foundation
2014: Member of the Leopoldina
2016: Member of the Medical Review Board of the DFG

Web links

Literature by and about Christian Kurts in the catalog of the German National Library
Institute homepage
Bonn: When the immune system fights its own kidneys. Press release about a study on dendritic cells of the kidney
Poison, digest, or commit suicide? Press release on a study on antigen presentation

Individual evidence

↑ C. Kurts, WR Heath, FR Carbone, J. Allison, JF Miller, H. Kosaka: Constitutive class I-restricted exogenous presentation of self antigens in vivo. In: J Exp Med . 184, 1996, pp. 923-930.
↑ C. Kurts, H. Kosaka, FR Carbone, JFAP Miller, WR Heath: Exogenous class I-restricted cross-presentation of self antigens can lead to deletion of autoreactive CD8 + T cells. In: J Exp Med. 186, 1997, pp. 239-245.
↑ T. Kruger, D. Benke, F. Eitner, A. Lang, M. Wirtz, EE Hamilton-Williams, DR Engel, B. Giese, G. Muller-Newen, J. Floege, C. Kurts: Identification and functional characterization of dendritic cells in the healthy murine kidney and in experimental glomerulonephritis. In: J Am Soc Nephrol . 15, 2004, pp. 613-621.
^ S. Burgdorf, A. Kautz, V. Böhnert, PA Knolle, C. Kurts: Distinct antigen uptake and intracellular routing mechanisms in CD4 and CD8 T cell activation. In: Science . 316, 2007, pp. 612-616.
↑ C. Kurts, BWS Robinson, PA Knolle: Cross-priming in Health and Disease. In: Nat Rev Immunol . 10 (6), 2010, pp. 403-414.
↑ V. Semmling, V. Lukacs Kornek, CA Thaiss, T. Quast, K. Hochheiser, U. tanks, J. Ross John P. Perlmutter, J. Cao, DI Godfrey, PB Savage, PA tuber, W. Kolanus , I. Förster, C. Kurts: Alternative cross-priming through CCL17-CCR4-mediated CTL attraction towards NKT cell-licensed dendritic cells. In: Nat Immunol . 11 (4), 2010, pp. 313-320.
^ F. Heymann, C. Meyer-Schwesinger, EE Hamilton-Williams, L. Hammerich, U. Panzer, S. Kaden, J. Floege, HJ Gröne, C. Kurts: Kidney dendritic cell activation is required for progression of renal disease in a mouse model of glomerular injury. In: J Clin Invest. 119, 2009, pp. 1286-1297.
^ DR Engel, A. Koscielny, S. Wehner, J. Maurer, M. Schiwon, B. Schumak, A. Limmer, T. Sparwasser, A. Hirner, PA Knolle, JC Kalff, C. Kurts: Th1 memory cells disseminate postoperative ileus over the entire intestinal tract. In: Nat Med . 16 (12), 2010, pp. 1407-1413.
↑ C. Kurts, BWS Robinson, PA Knolle: Cross-priming in Health and Disease. In: Nat Rev Immunol . 10 (6), 2010, pp. 403-414.
↑ C. Kurts, U. Panzer, HJ Anders, A. Rees: The immune system and kidney disease: basic concepts and clinical implications. In: Nat Rev Immunol . 13 (10), 2013, pp. 738-753.
↑ M. Schiwon, C. Kurts, D. Engel: Crosstalk between sentinel and helper macrophages permits neutrophil migration into infected uroepithelium. In: Cell . 156, 2014, pp. 456-468.
↑ Member entry by Prof. Dr. Christian Kurts (with picture and CV) at the German Academy of Sciences Leopoldina , accessed on June 7, 2016.

personal data
SURNAME	Kurts, Christian
BRIEF DESCRIPTION	German university professor and immunologist
DATE OF BIRTH	November 27, 1964
PLACE OF BIRTH	Helmstedt

[1] C. Kurts, WR Heath, FR Carbone, J. Allison, JF Miller, H. Kosaka: Constitutive class I-restricted exogenous presentation of self antigens in vivo. In: J Exp Med . 184, 1996, pp. 923-930.

[2] C. Kurts, H. Kosaka, FR Carbone, JFAP Miller, WR Heath: Exogenous class I-restricted cross-presentation of self antigens can lead to deletion of autoreactive CD8 + T cells. In: J Exp Med. 186, 1997, pp. 239-245.

[3] T. Kruger, D. Benke, F. Eitner, A. Lang, M. Wirtz, EE Hamilton-Williams, DR Engel, B. Giese, G. Muller-Newen, J. Floege, C. Kurts: Identification and functional characterization of dendritic cells in the healthy murine kidney and in experimental glomerulonephritis. In: J Am Soc Nephrol . 15, 2004, pp. 613-621.

[4] S. Burgdorf, A. Kautz, V. Böhnert, PA Knolle, C. Kurts: Distinct antigen uptake and intracellular routing mechanisms in CD4 and CD8 T cell activation. In: Science . 316, 2007, pp. 612-616.

[5] C. Kurts, BWS Robinson, PA Knolle: Cross-priming in Health and Disease. In: Nat Rev Immunol . 10 (6), 2010, pp. 403-414.

[6] V. Semmling, V. Lukacs Kornek, CA Thaiss, T. Quast, K. Hochheiser, U. tanks, J. Ross John P. Perlmutter, J. Cao, DI Godfrey, PB Savage, PA tuber, W. Kolanus , I. Förster, C. Kurts: Alternative cross-priming through CCL17-CCR4-mediated CTL attraction towards NKT cell-licensed dendritic cells. In: Nat Immunol . 11 (4), 2010, pp. 313-320.

[7] F. Heymann, C. Meyer-Schwesinger, EE Hamilton-Williams, L. Hammerich, U. Panzer, S. Kaden, J. Floege, HJ Gröne, C. Kurts: Kidney dendritic cell activation is required for progression of renal disease in a mouse model of glomerular injury. In: J Clin Invest. 119, 2009, pp. 1286-1297.

[8] DR Engel, A. Koscielny, S. Wehner, J. Maurer, M. Schiwon, B. Schumak, A. Limmer, T. Sparwasser, A. Hirner, PA Knolle, JC Kalff, C. Kurts: Th1 memory cells disseminate postoperative ileus over the entire intestinal tract. In: Nat Med . 16 (12), 2010, pp. 1407-1413.

[9] C. Kurts, BWS Robinson, PA Knolle: Cross-priming in Health and Disease. In: Nat Rev Immunol . 10 (6), 2010, pp. 403-414.

[10] C. Kurts, U. Panzer, HJ Anders, A. Rees: The immune system and kidney disease: basic concepts and clinical implications. In: Nat Rev Immunol . 13 (10), 2013, pp. 738-753.

[11] M. Schiwon, C. Kurts, D. Engel: Crosstalk between sentinel and helper macrophages permits neutrophil migration into infected uroepithelium. In: Cell . 156, 2014, pp. 456-468.

[12] Member entry by Prof. Dr. Christian Kurts (with picture and CV) at the German Academy of Sciences Leopoldina , accessed on June 7, 2016.