Club cell
The Club-cell , also dt. Lobe cell , formerly Clara cell , is a specialized type of cell in the bronchioles of the lungs occurs. These are secretory cells of the distal airways (bronchioli terminales, respiratorii and ductus alveolares), which have granules containing secretions and large, species-dependent differences.
The Clara cell is named after the South Tyrolean doctor and anatomist Max Clara (1899–1966), who dissected people executed in Leipzig for his scientific work. Due to Clara's ingratiation to the NSDAP , attempts are being made to delete the term Clara cell and replace it with club cells or secretory cells of the distal airways .
It is certain that they secrete, among other things, surfactant proteins and also lysozyme , which are necessary for the unspecific defense. They have cytochrome P450 enzymes which also play a role in detoxifying any inhaled toxins. It is assumed that they produce a glycoprotein-containing secretion in humans , which is involved in keeping the small airways open.
Individual evidence
- ^ Excerpt from Pathology of the Lung , Springer Verlag on Google Books
- ↑ Süddeutsche Zeitung. September 29, 2010, p. 16.
- ^ Disease names used by Nazi doctors
- ↑ Renate Lüllmann-Rauch: Histology . 5th edition. Georg Thieme Verlag, Stuttgart / New York, ISBN 978-3-13-129245-2 , p. 379 .
- ↑ U. Welsch: Sobotta textbook histology, cytology, histology, microscopic anatomy. Urban & Fischer-Verlag, 2006, ISBN 3-437-44430-1 , p. 322. (online)
- ^ R. Lüllmann-Rauch: pocket textbook histology. Thieme Verlag, 2006, ISBN 3-13-129242-3 , p. 334 f.