The p 2
| Mite group 2 allergen The p 2 | ||
|---|---|---|
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| according to PDB 1A9V | ||
| other names |
Allergen Der p II, DPX, Allergen: Der p 2 |
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| Mass / length primary structure | 146 amino acids , 15,999 Da | |
| Identifier | ||
| External IDs | ||
The p 2 is a protein from the European house dust mite Dermatophagoides pteronyssinus . It is one of the major house dust allergens of people .
properties
The p 2 has a homology to the toll-like receptor MD-2 . Besides Der p 1 , it is the main house dust allergen of Dermatophagoides pteronyssinus and occurs in over 80% of house dust allergy sufferers with reactions to D. pteronyssinus . In house dust allergy sufferers, antibodies of the immunoglobulin E type are formed, which are used for diagnosis .
Web links
Individual evidence
- ↑ a b c J. C. Bessot, G. Pauli: Mite allergens: an overview. In: European annals of allergy and clinical immunology. Volume 43, Number 5, October 2011, pp. 141-156, PMID 22145250 .
- ↑ X. Yang, G. Fan, J. Li: Diagnostic value of Der p 1 and Der p 2 specific IgE in Dermatophagoides pteronyssinus IgE sensitization. In: Annals of allergy, asthma & immunology: official publication of the American College of Allergy, Asthma, & Immunology. Volume 116, Number 4, April 2016, pp. 295-301, doi : 10.1016 / j.anai.2016.02.010 , PMID 27055990 .