Diabetic angiopathy

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Classification according to ICD-10
E10-E14 Diabetes mellitus
.2+

N08.3 *
With kidney complications
- diabetic nephropathy
glomerular diseases in diabetes mellitus
.3+

H36.0 *
With eye complications
- diabetic retinopathy
Retinopathia diabetica
.4+
G99.0 *

G59.0 *
G63.2 *
With neurological complications
Autonomic neuropathy in endocrine and metabolic diseases
Diabetic mononeuropathy
Diabetic polyneuropathy
.5+

I79.2 *
With peripheral vascular complications,
Diabetic Peripheral Angiopathy.
Peripheral Angiopathy in Diseases Classified Elsewhere
- Diabetic Peripheral Angiopathy
I70 Atherosclerosis
ICD-10 online (WHO version 2019)

Vascular damage that occurs as a late complication in diabetes mellitus is referred to as diabetic angiopathy .

Changes in the capillaries ( microangiopathy ) cause various forms of diabetic microangiopathy : in particular diabetic nephropathy (kidney disease), diabetic retinopathy (eye disease) and autonomic neuropathy (disease of the peripheral nervous system).

Although macroangiopathy is not diabetic-specific, it occurs more quickly and more strongly than in non-diabetics, which is why the term diabetic macroangiopathy is common. It leads to atherosclerotic changes in medium and large arteries. It is responsible for the high risk of heart attack , stroke and gangrene in diabetes.

The main factors that promote the development of micro- and macroangiopathy in diabetics are hyperglycemia , hyperlipoproteinemia , insulin resistance, and various vasoactive hormones , cytokines, and growth factors .

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  • Alvin C. Powers (for the German edition: Elke Austenat and Sabine Semmler). Diabetes mellitus. In: Harrison's Internal Medicine. German Edition of the 15th edition, ABW-Wissenschaftsverl., Berlin 2003, ISBN 3-936072-10-8