Emivirin

Structural formula
General
Non-proprietary name	Emivirin
other names	6-benzyl-1- (ethoxymethyl) -5-isopropyluracil 1- (ethoxymethyl) -6- (phenylmethyl) -5-propan-2-ylpyrimidin-2,4-dione
Molecular formula	C 17 H 22 N 2 O 3
External identifiers / databases
CAS number 149950-60-7 PubChem 65013 ChemSpider 58529 DrugBank DB08188 Wikidata Q906062
Drug information
Drug class	Antivirals non-nucleoside reverse transcriptase inhibitors
Mechanism of action	allosteric inhibition of reverse transcriptase
properties
Molar mass	302.37 g mol −1
safety instructions
GHS hazard labeling no classification available
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Emivirin (Coactinon, MKC-442) is a non-nucleoside reverse transcriptase inhibitor . However, work on the active ingredient was discontinued by Triangle Pharmaceuticals as no improved effectiveness could be demonstrated. The drug should be used to treat HIV .

pharmacology

Emivirin attaches itself to a region of reverse transcriptase that is adjacent to the catalytic center and allosterically inhibits the enzyme .

literature

• Tanaka, Takashima, Journal of Medicinal Chemistry 1995, Vol 38, No 15, p. 2864
• Szczech, Furman, Painter, et al. a., Antimicrobial agents and chemotherapy , 44 (1), 123-130 dAN 2000

Individual evidence

1. ↑ This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.

This article is about a health issue. It is not used for self-diagnosis and does not replace a diagnosis by a doctor. Please note the information on health issues !