Darifenacin

from Wikipedia, the free encyclopedia
Structural formula
Structural formula of darifenacin
General
Non-proprietary name Darifenacin
other names

( S ) -2- (1- [2- (2,3-Dihydrobenzofuran-5-yl) ethyl] -3-pyrrolidinyl) -2,2-diphenyl-acetamide ( IUPAC )

Molecular formula C 28 H 30 N 2 O 2
External identifiers / databases
CAS number 133099-04-4
EC number 603-704-1
ECHA InfoCard 100.118.382
PubChem 444031
DrugBank DB00496
Wikidata Q166476
Drug information
ATC code

G04 BD10

Drug class

Urinary tract antispasmodics

properties
Molar mass 426.55 g mol −1
safety instructions
Please note the exemption from the labeling requirement for drugs, medical devices, cosmetics, food and animal feed
GHS hazard labeling
no classification available
As far as possible and customary, SI units are used. Unless otherwise noted, the data given apply to standard conditions .

Darifenacin is an organic chemical compound from the aromatic class , which is used under the trade name Emselex ® (manufacturer Novartis ) as a medicinal substance for the treatment of urinary incontinence .

Pharmacological properties

Mechanism of action (pharmacodynamics)

Darifenacin is a selective M 3 -Acetylcholinrezeptor - antagonist .

Trade names

Monopreparations

Emselex (D, A, CH), Enablex (USA, CDN)

Web links

literature

  • Speir JP, Perkins G., Berg C., Pullen F., Billerica, In: Rapid Communications in Mass Spectrometry , 14 / (20), 2000, pp. 1937-1942
  • Venn RF, Goody RJ, In: Chromatographia , 50 / (7/8), 1999, pp. 407-414
  • Miyamae K., Yoshida M., Murakami S., Iwashita H., Ohtani M., Masungana K., Ueda S., In: Pharmacology 69 / (4), 2003, pp. 205-211

Individual evidence

  1. ↑ This substance has either not yet been classified with regard to its hazardousness or a reliable and citable source has not yet been found.
  2. ↑ Red List Online, as of August 2009.
  3. ↑ AM comp. d. Switzerland, as of August 2009.
  4. ↑ AGES-PharmMed, as of August 2009.