Eric Topol

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Eric Topol

Eric J. Topol (born June 26, 1954 ) is an American cardiologist and author.

Topol studied medicine at the University of Virginia with a bachelor's degree in 1975 and from the University of Rochester with an MD. He completed his residency at the University of California, San Francisco and his fellowship in cardiology at Johns Hopkins University . From 1985 to 1991 he taught at the University of Michigan before becoming director of cardiology at the Cleveland Clinic . There he developed cardiology into a leading position in the USA and founded the first cardiological gene database in 1996. In 2002 he founded the Cleveland Clinic Lerner College of Medicine and was its Chief Academic Officer until 2006. In 2003 he became Professor of Genetics at Case Western Reserve University . At the end of 2006, he moved to the Scripps Research Institute as Professor of Genetics, where he founded the Scripps Research Translational (Scripps Translational Science Institute, STSI) specializing in personalized medicine . He is also the Chief Academic Officer of Scripps Health.

His move from Cleveland Clinic also had to do with a dispute with the management of the clinic in connection with Topol's early criticism of the cardiac side effects of Vioxx (rofecoxib), which Merck eventually withdrew as a drug for these reasons in 2004 .

Significant scientific findings could be gained from the gene database he initiated on cardiovascular diseases and Topol identified several genes that increase the predisposition to heart attacks. This was recognized with the election in the Top 10 Advances of the American Heart Association and the Top Medical Breakthrough for 2010 by TIME Magazine.

In 2009, he and Gary and Mary West founded the West Wireless Health Institute (West Health Institute), which is dedicated to digitization in medicine. He was active in the wireless monitoring of patients early on, for example with CardioNet (wireless monitoring of the EKG) in 1999. In 2007 he was on the board of directors of Sotera Wireless (wireless monitoring of high blood pressure and other vital signs).

He is the proponent of personalized medicine with genome analysis, new digital methods and biosensors.

Topol led clinical studies on genetically engineered t-PA , the monoclonal antibody abciximab, and the platelet inhibitor clopidogrel (Plavix).

He wrote several bestsellers on the future of medicine, the role of digitization and artificial intelligence in medicine.

He is editor-in-chief of Medscape , a web-based information and education system for doctors.

In 2004 he became a member of the Institute of Medicine of the National Academy of Sciences . He received the Hutchinson Medal from his alma mater, the University of Rochester. In 2011, a cardiology chair at the University of Michigan was named after him.

Topol is among the ten most cited scientists in medicine according to Thompson Reuters ISI. He is the author or co-author of over 1100 publications.

Fonts

  • The Patient Will See You Now: The Future of Medicine Is in Your Hands , New York: Basic Books, 2015
  • The Creative Destruction of Medicine: How the Digital Revolution Will Create Better Health Care , New York: Basic Books, 2012
  • with others: Textbook of cardiovascular medicine , Lippincott, Williams and Wilkins 2002
  • Editor: Acute coronary syndroms , Marcel Dekker, 3rd edition, 2004
  • with Paul S. Teirstein: Textbook of Interventional Cardiology , Philadelphia, Elsevier, 8th edition 2019
  • Deep Medicine. How Artificial Intelligence Can Make Healthcare Human Again , 2019
  • with Leonard J. Kish: Unpatients - why patients should own their medical data, Nature Biotechnology, Volume 33, 2015, pp. 921-924
  • Individualized Medicine from Prewomb to Tomb, Cell, Volume 157, Issue 1, March 27, 2014

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