Fiona Powrie

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Fiona Powrie

Fiona M. Powrie (* 1963 in Luton ) is a British biochemist and immunologist (especially immunology of the intestinal tract).

Powrie studied biochemistry at Bath University and received his PhD in immunology from Don Mason at Oxford . As a post-doctoral student , she was with Robert L. Coffman in the USA. In 1996 she got her own laboratory in Oxford (funded by the Wellcome Trust) and in 2009 she became Sidney Truelove Professor of Gastroenterology there . She is a professor at Oxford University and director of the Kennedy Institute of Rheumatology there. She is also the Principal Investigator of the Translational Gastroenterology Unit in Oxford.

Powrie deals with the interaction and the fragile balance of the immune system with the intestinal flora and its disruption in intestinal infections with the result of inflammatory reactions. She showed the role of certain regulatory T lymphocytes (Treg) in the balance between the immune system and intestinal flora (especially in protecting the beneficial intestinal bacteria) and showed that both the innate and the acquired immune system play a role in intestinal inflammation and that interleukin 23 plays a crucial role the development of chronic intestinal inflammation plays a role. In animal experiments, a deficiency of certain Tregs leads to chronic intestinal inflammation and to maintain the balance in the intestine, different types of Treg must work in opposite directions. She is also exploring the possibility of treating intestinal inflammation with regulatory T lymphocytes.

In 2012 she received the Louis Jeantet Prize . She also received the Ita Askonas Prize from the European Federation of Immunological Societies.

She is a Fellow of the Royal Society (2011) and the Academy of Medical Sciences and is a member of the European Molecular Biology Organization and Academia Europaea . In 2020 she was elected to the National Academy of Sciences .

Web links

Individual evidence

  1. ↑ Acknowledgment at the Louis Jeantet Prize , French
  2. ^ Membership directory: Fiona Powrie. Academia Europaea, accessed January 6, 2018 .
personal data
SURNAME Powrie, Fiona
ALTERNATIVE NAMES Powrie, Fiona M.
BRIEF DESCRIPTION British biochemist and immunologist
DATE OF BIRTH 1963
PLACE OF BIRTH Luton