Fritz Anders (geneticist)

from Wikipedia, the free encyclopedia

Fritz Anders (born November 22, 1919 in Berlin ; † December 21, 1999 in Gießen ) was a German geneticist and molecular biologist. He was a professor at the University of Giessen .

Life

Anders grew up in Wentdorf and, after doing military service in World War II and being a prisoner of war in the Soviet Union, studied pedagogy in Potsdam from 1949 onwards and then biology at the University of Mainz , where he received his doctorate in 1954. His dissertation was on sex determination by multiple genes in lower animals. In the same year he married the geneticist Annerose Anders. After completing his doctorate, he was at the Geilweilerhof grapevine breeding institute, where he dealt with plant tumors. He completed his habilitation on the same subject in Saarbrücken. In 1964 he became a professor in Giessen, where he founded and headed the Genetic Institute. In 1988 he retired.

He dealt with tumor genetics and was one of the pioneers in Germany. He began by cross-breeding experiments with fish, one line of which passed on skin cancer, something that Myron Gordon of New York had already researched. Anders was able to demonstrate the existence of oncogenes and tumor suppressor genes that counteract the oncogenes. He worked with his wife Annerose Anders and used tooth carp as laboratory animals. In 1977 he suggested that cancer in some human tumors is caused by loss or impairment of suppressor genes. In 1989 he presented an evolutionary tree of cancer genes. He characterized various cancer genes and tested various carcinogens . In 1999, he discovered a new type of genetic cause for cancer, which he called paragenetic, as it was not inherited in the classic way (they correspond to retrotransposons ).

In 1987 he became a member of the Leopoldina . The Society for Genetics awards him the Fritz Anders Prize for students of genetics in his honor.

Fonts

  • A Biologist's View of Human Cancer, Dr Mildred Scheel Memorial Lecture, in Neth, Gallo u. a. Modern trends in human leukemia VIII, Springer 1989, pp. 23–45
  • with A. Anders: Etiology of cancer as studied in the platyfish-swordtail system, Biochim. Biophys. Acta, Vol. 516, 1978, pp. 61-95
  • with J. Roushdy, J. Michel, H. Petry, A. Anders: Paragenetic suppressors of suppressor genes - a new class of oncodeterminants, J. Cancer Res. Clin. Oncol., Vol. 125, 1999, pp. 123-133
  • Tumor formation in platyfish-swordtail hybrids as a problem of gene regulation, Experientia, 23, 1967, pp. 1-10

Web links

References and comments

  1. ^ List of members Leopoldina, Fritz Anders
  2. ^ Fritz Anders Prize
personal data
SURNAME Different, Fritz
BRIEF DESCRIPTION German geneticist and molecular biologist
DATE OF BIRTH November 22, 1919
PLACE OF BIRTH Berlin
DATE OF DEATH December 21, 1999
Place of death to water