Fusobacterium necrophorum

Fusobacterium necrophorum
Systematics
Department :	Fusobacteria
Class :	Fusobacteriia
Order :	Fusobacteriales
Family :	Fusobacteriaceae
Genre :	Fusobacterium
Type :	Fusobacterium necrophorum
Scientific name
	Fusobacterium necrophorum
	( Flügge 1886) Moore & Holdeman 1969

Fusobacterium necrophorum is a gram-negative , non-spore-forming, obligately anaerobic, thread-like rod-shaped bacterium which, like other Fusobacteria, belongs to the Fusobacteriaceae family. Like all bacteria belonging to this family, they belong to the normal flora (especially in the oropharynx, intestines and genital tract) of humans. F. necrophorum is found mainly in the mouth. Infection processes therefore usually occur endogenously and usually in the form of mixed infections. Monoinfections are less common, but are often characterized by severe forms (e.g. sepsis ).

Medical importance

Fusobacterium species can cause bacteremia and abscesses in humans. Both Ludovici angina and Lemierre syndrome are mainly caused by Fusobacterium necrophorum .

In horses , it causes thrush . When cattle the seed has in addition to the initiation of multiple liver abscesses and infection of the genital organs strong importance as pathogens of mouth inflammation and Kälberdiphteroids in sheep and goats , he releases the foot rot of. In addition, Fusobacterium necrophorum is the cause of lumpy jaw disease in kangaroos , the most common and lossy disease of captive kangaroos .

The antibiotics metronidazole , ampicillin sulbactam and amoxicillin calvulanic acid as well as alternatively clindamycin and imipenem are suitable for the antimicrobial therapy of infections with fusobacteria .

literature

Schulz LC (ed.): Pathology of domestic animals. Part II: Diseases and Syndromes. Gustav Fischer Verlag Jena, 1991 75-76
C. Spitzer et al. Bacterial meningitis as a complication of Fusobacterium necroforum sepsis in adults. The neurologist. Volume 74, Number 12 / December 2003 doi : 10.1007 / s00115-003-1580-8
W. Köhler et al .: Medical Microbiology. Urban & Fischer-Verlag Munich / Jena 2001, 8th edition, p. 376 ff. ISBN 3-437-41640-5
H. Selbitz et al .: Medical microbiology, infection and epidemic science. Enke Verlag Stuttgart 2011 p. 87 ISBN 978-3-8304-1080-5 .

Individual evidence

^ Marianne Abele-Horn: Antimicrobial Therapy. Decision support for the treatment and prophylaxis of infectious diseases. With the collaboration of Werner Heinz, Hartwig Klinker, Johann Schurz and August Stich, 2nd, revised and expanded edition. Peter Wiehl, Marburg 2009, ISBN 978-3-927219-14-4 , p. 263.
^ Marianne Abele-Horn (2009).

[1] Marianne Abele-Horn: Antimicrobial Therapy. Decision support for the treatment and prophylaxis of infectious diseases. With the collaboration of Werner Heinz, Hartwig Klinker, Johann Schurz and August Stich, 2nd, revised and expanded edition. Peter Wiehl, Marburg 2009, ISBN 978-3-927219-14-4 , p. 263.

[2] Marianne Abele-Horn (2009).