Gliadin
α- / β-gliadin | ||
---|---|---|
Surface model of immunoglobulin HLA-DQ complexed with gliadin according to PDB 1S9V | ||
Mass / length primary structure | 266 amino acids | |
Identifier | ||
Gene name (s) | GDA | |
External IDs | ||
Occurrence | ||
Parent taxon | wheat |
γ-gliadin | ||
---|---|---|
Mass / length primary structure | 285 amino acids | |
Identifier | ||
Gene name (s) | GDB | |
External IDs |
ω-gliadin | ||
---|---|---|
Mass / length primary structure | 280 amino acids | |
Identifier | ||
Gene name (s) | GDO | |
External IDs |
As gliadin all be alcohol -soluble storage proteins of wheat , respectively. They are divided into α- / β-, γ- and ω-gliadins according to their solubility. The α- / β- and γ-gliadins are antigens responsible for celiac disease in humans, but the ω-gliadins can also trigger allergic reactions .
In contrast to glutenin , a second Osborne fraction , gliadin is soluble in 70 percent ethanol and can be fractionated accordingly. Gliadin has a molecular mass of <100,000 u . In the primary amino acid sequence, the amino acids proline and glutamine predominate ; the nutritionally important and essential amino acid lysine is less strongly represented than in the osborn fractions albumin and globulin . Genetically, the α- / β-gliadins are divided into five and the γ-gliadins into three homology classes. Each haploid genome contains over 100 copies of the coding gene for α- / β-gliadin.
Gliadin is highly elastic and not very elastic. When making wheat-based baked goods, it strengthens the dough together with the gluten and stabilizes the crumb after baking with the gelatinized starch .
Individual evidence
- ↑ Walter Bushuk, Vladimir F. Rasper: Wheat: Production, Properties and Quality . Blackie Academic and Professional, Glasgow 1994, ISBN 0-7514-0181-1 , pp. 76 ff .
- ↑ UniProt P02863
- ↑ Sumner-Smith M, Rafalski JA, Sugiyama T, Stoll M, Söll D: Conservation and variability of wheat alpha / beta-gliadin genes . In: Nucleic Acids Res . 13, No. 11, June 1985, pp. 3905-916. PMID 3839304 . PMC 341285 (free full text).
Web links
- Interpro: IPR001376 Gliadin, alpha / beta