Granuloma annulare
| Classification according to ICD-10 | |
|---|---|
| L92.0 | Granuloma annulare |
| ICD-10 online (WHO version 2019) | |
Granuloma annulare is one of the non-infectious granulomatous skin diseases that show up in centrifugally spreading papules . Symptoms are ring-shaped, small, non-itchy, sharply demarcated and slightly reddish papules that get larger over time. The exact cause of the disease is not known. It occurs predominantly in childhood and in women. Individual case reports of familial occurrences are known.
Granuloma annulare mainly occurs on the acres , i.e. on the back of the feet and hands, as well as over the joints. From a differential diagnostic point of view, annular sarcoid disease (Boeck's disease) , necrobiosis lipoidica or rheumatic nodules must be considered. If there are only individual foci on the hand, a foreign body granuloma can be ruled out. The granuloma annulare may arise as a result of post-infectious circulating immune complexes or cell-mediated immune mechanisms. In the rare Melkersson-Rosenthal syndrome, a wrinkled tongue , swelling of the upper or lower lip and recurrent facial paralysis occur. An association of 20% with diabetes mellitus was previously found in those affected . However, recent studies refute this.
Healing almost always takes place without scarring, but this disease is very persistent and to date no long-term effective treatment is known. Moderately successful treatment methods are exposure to UV light , film bandages containing cortisol, and cryotherapy to disrupt the ring structure. In more severe cases, intralesional cortisol therapy may be indicated. It is also important to let the foci of inflammation heal.
Web links
- Granuloma annulare. DermIs
- Granuloma annular and autoimmune thyroid disease (PDF; 116 kB)
- Diagnosis and Management of Granuloma Annulare. AAFP, 2006
Individual evidence
- ↑ Granuloma annulare (overview). In: Dermatology - Altmeyer's Encyclopedia. Retrieved August 29, 2017 .
