Harold F. Dvorak
Harold Fisher Dvorak (born June 20, 1937 in Milwaukee , Wisconsin ) is an American pathologist and vascular researcher . He is best known for his discovery of the Vascular Endothelial Growth Factor (VEGF).
Live and act
Dvorak received his medical degrees from Princeton University and Harvard University . He trained as a pathologist at the Massachusetts General Hospital . As a postdoctoral fellow , he went to the National Institutes of Health . In 1967 he was admitted to the faculty at Harvard University, where he now holds the title of Mallinckrodt Distinguished Professor of Pathology . Since 1979 he has also worked at the Beth Israel Deaconess Medical Center (BIDMC), a teaching hospital at Harvard Medical School, where he founded the Center for Vascular Biology Research . Until 2006 he was also head of the pathology department there.
Dvorak is primarily concerned with angiogenesis , especially of tumors, which he considers to be similar to that of wound healing . In 1983 Dvorak discovered the Vascular Permeability Factor , VPF (later renamed Vascular Endothelial Growth Factor , VEGF), which is a central regulatory function in the formation of new blood vessels and serves as a target molecule for new forms of therapy in cancer and wet macular degeneration . He was an editor of the journal Cancer Research and has published more than 220 scientific papers .
Awards (selection)
- 1999 Fellow of the American Association for the Advancement of Science
- 2002 ASIP Rous-Whipple Award from the American Society for Investigative Pathology (ASIP)
- 2006 Szent-Györgyi Prize of the National Foundation for Cancer Research
- 2014 Canada Gairdner International Award
literature
- D. Ribatti: The contribution of Harold F. Dvorak to the study of tumor angiogenesis and stroma generation mechanisms. In: Endothelium: journal of endothelial cell research. Volume 14, Number 3, 2007 May-Jun, pp. 131-135, ISSN 1062-3329 . doi: 10.1080 / 10623320701421651 . PMID 17578706 . Reprinted in Domenico Ribatti: Protagonists of Medicine. Springer 2010 ISBN 978-90-481-3741-1 limited preview in the Google book search
Web links
- Harold F. Dvorak, MD and Harold Dvorak Lab at Beth Israel Deaconess Medical Center (bidmc.org)
- Harold F. Dvorak, MD at the National Foundation of Cancer Research (nfcr.org)
Individual evidence
- ↑ Curriculum Vitae Harold Fisher Dvorak, MD . Legacy Tobacco Documents Library, University of California, San Francisco; Retrieved April 10, 2014.
- ↑ Dvorak, Harold. In: aaas.org. May 11, 2017, accessed April 14, 2018 .
- ^ Rous-Whipple Award 2002 (PDF, 52 kB) from the American Society for Investigative Pathology (asip.org); accessed on March 26, 2014
- ↑ BIDMC's Harold Dvorak, MD, honored by National Foundation for Cancer Research at eurekalert.org; accessed on March 26, 2014
- ↑ Harold F. Dvorak at the Gairdner Foundation (gairdner.org); accessed on March 26, 2014
| personal data | |
|---|---|
| SURNAME | Dvorak, Harold F. |
| ALTERNATIVE NAMES | Dvorak, Harold Fisher (full name) |
| BRIEF DESCRIPTION | American pathologist and vascular researcher |
| DATE OF BIRTH | June 20, 1937 |
| PLACE OF BIRTH | Milwaukee , Wisconsin |