Howard E. Skipper
Howard Earle Skipper (born November 21, 1915 in Avon Park , Florida , † January 2, 2006 in Mountain Brook , Alabama ) was an American oncologist .
resume
Skipper grew up as the son of Chesley Allen Skipper and Estelle Wiggins Skipper in Sebring (Florida). In his youth he worked on his father's cattle ranch. After graduating from high school, he studied at the University of Florida . In 1938 he became a Bachelor of Science and a year later a Master of Science . In 1941 he was promoted to Dr. phil. PhD in biochemistry and nutrition . During the Second World War he worked from 1941 to 1945 in the Chemical Warfare Service (from 1945 Chemical Corps ). His interest in oncology began during the war, through his handling of the warfare agent nitrogen mustard . Skipper was convinced that this compound also had an active ingredient potential. After the war, Skipper went to the Southern Research Institute (SRI) to set up biochemical research. In 1949 he became head of the department for organic chemistry and biochemistry, 1964 vice-president of the SRI and 1974 president of the institute. In parallel, Skipper was Professor of Experimental Pathology and Professor of Research Medicine at the University of Alabama . At the SRI, Skipper developed new treatment protocols for chemotherapy . In doing so, he made fundamental discoveries and, among other things, put forward the hypothesis of the log cell kill . Skipper published over 200 scientific papers.
Howard E. Skipper married Margaret T. Edwards in 1940 , whom he met at the University of Florida. His wife died in 1984. The marriage had two children, Howard Earle Jr. and Margaret Ann Skipper .
Awards
- 1974 Albert Lasker Award for Basic Medical Research
- 1982 Kettering Prize
- 1982 American Cancer Society Annual National Award
Publications (selection)
- HE Skipper: Laboratory models: some historical perspective. In: Cancer Treat Rep 70, 1986, pp. 3-7. PMID 3943114
- HE Skipper: Combination therapy: some concepts and results. In: Cancer Chemother Rep 2, 1974, pp. 137-145. PMID 4363649
- HE Skipper: Cancer chemotherapy is many things: GHA Clowes Memorial Lecture. In: Cancer Res 31, 1971, pp. 1173-1180. PMID 5115048
- HE Skipper and S. Perry: Kinetics of normal and leukemic leukocyte populations and relevance to chemotherapy. In: Cancer Res 30, 1970, pp. 1883-1897. PMID 4917694 (Review)
- HE Skipper: The effects of chemotherapy on the kinetics of leukemic cell behavior. In: Cancer Res 25, 1965, pp. 1544-1550. PMID 5861078
literature
- L. Simpson-Herren and GP Wheeler Howard Earle Skipper: In Memoriam (1915-2006). In: Cancer Res 66, 2006, p. 12035. doi : 10.1158 / 0008-5472.CAN-06-3615
Individual evidence
- ^ HE Skipper: Perspectives in Cancer Chemotherapy: Therapeutic Design. In: Cancer Res 24, 1964, pp. 1295-1302. PMID 14221786
| personal data | |
|---|---|
| SURNAME | Skipper, Howard E. |
| ALTERNATIVE NAMES | Skipper, Howard Earle |
| BRIEF DESCRIPTION | American oncologist |
| DATE OF BIRTH | November 21, 1915 |
| PLACE OF BIRTH | Avon Park , Florida |
| DATE OF DEATH | January 2, 2006 |
| Place of death | Mountain Brook , Alabama |