Hypogonadotropic hypogonadism
| Classification according to ICD-10 | |
|---|---|
| E23.0 | Hypopituitarism - Hypogonadotropic hypogonadism |
| ICD-10 online (WHO version 2019) | |
As hypogonadotropic hypogonadism an underactive is gonads designated by the lack of excitation of the part glandotropic hormones FSH and LH is conditional.
Possible causes of hypogonadotropic hypogonadism are:
- a dysfunction of the hypothalamus (tertiary hypogonadism, see also olfactogenital syndrome or Kallmann syndrome )
- Disruption of the hypothalamo-pituitary portal vasculature in the context of Pickardt's syndrome (intermediate form between secondary and tertiary hypogonadism)
- Damage to the pituitary gland , e.g. B. Sheehan's syndrome or pituitary adenoma (secondary hypogonadism)
- functional hypogonadism, often due to hyperprolactinemia
- pronounced and prolonged malnutrition due to anorexia , the anorexia nervosa
- congenital (innate) forms, e.g. B. in Pasqualini syndrome or Richards-Rundle syndrome
See also
- KiSS1 receptor ( puberty gene )
- Kisspeptin