James Bruce Bussel

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James Bruce Bussel (born before 1975) is an American medical doctor ( pediatrics ).

Life

Bussel studied at Yale University ( bachelor's degree) and the College of Physicians and Surgeons at Columbia University (MD degree in 1975). He completed his residency at the Cincinnati Childrens Hospital and was then a Fellow in Pediatric Oncology and Hematology at the Memorial Sloan-Kettering Cancer Center and at the New York-Presbyterian Hospital at Cornell University , where he was Chief Fellow in 1980/81. He is Professor of Pediatrics at Weill Cornell Medical College, Cornell University.

Since the 1980s, he has been developing therapies against the autoimmune disease ITP, which manifests itself as a platelet deficiency, in children and adults, and has directed clinical studies on this.

In 2012 he received the König Faisal Prize with Richard L. Berkowitz . Bussel worked with the New York gynecologist Berkowitz for more than two decades on the research and development of diagnostic methods and non-invasive therapeutic methods for alloimmune thrombocytopenia (FAIT in the fetus, NAIT in the newborn), in which the mother has antibodies against the blood platelets (thrombocytes ) of the embryo, which can lead to serious disabilities and deaths in the children (around 10% of cases in the event of non-treatment), as the platelet deficiency leads to bleeding. It occurs in around one in a thousand births, but was often recognized too late. Bussel developed a therapeutic method using the intravenous administration of immunoglobulins to the fetus in the womb.

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