Jean-Laurent Casanova
Jean-Laurent Casanova (born June 14, 1963 in Paris ) is a French medical doctor ( pediatric immunology ).
After graduating in medicine from the University of Paris V (René Descartes), Casanova completed an internship in internal medicine at the Hospital Saint Antoine and Pitié-Salpêtrière in Paris in 1987. In 1992 he received his PhD in immunology from the University of Paris VI (Pierre et Marie Curie) , having previously worked in Philippe Kourilsky's laboratory at the Pasteur Institute and the Cancer Research Institute in Lausanne. He then completed his specialist training in paediatrics at the Hôpital Necker-Enfants malades children's hospital. There he researched in the group of congenital immune deficiencies under Alain Fischer . In 1999 he became professor of pediatrics and head of the laboratory for human genetics of infectious diseases, which he founded with Laurent Abel . In 2008 he went to Rockefeller University as a professor and researcher at the Howard Hughes Medical Institute (2013).
Casanova explored why some children more prone to certain infectious diseases (such as mycobacteria - and pneumococcal infection, meningitis with herpes simplex , the Kaposi's sarcoma , tuberculosis, influenza, candidiasis ) than others and attributed this to defects of single genes (in In contrast to adults, where the susceptibility arises from the interaction of several defects). With Laurent Abel he identified various such defects in individual genes. The findings triggered a paradigm shift in the question of the causes of dispositions for certain infectious diseases. The findings also provide approaches for therapies based on genetic diagnostics and the targeted administration of certain cytokines.
In 2005 he was elected to the European Molecular Biology Organization . In 2004 he received the Lucien Dautrebande Pathophysiology Foundation Prize, in 2008 the Richard Lounsbery Award , 2009 the Oswald Avery Award from the Infectious Disease Society of America, 2010 the E. Mead Johnson Award from the Society for Pediatric Research, 2011 the InBev-Baillet Latour Health Prize and 2012 the Milstein Award. In 2014 he received the Robert Koch Prize and in 2015 he was elected to the National Academy of Sciences . For 2016 Casanova received the Stanley J. Korsmeyer Award and the Grand Prix INSERM .
Web links
- Jean-Laurent Casanova, MD, Ph.D. on the Rockefeller University website
Individual evidence
- ↑ Jean-Laurent Casanova. Curriculum vitae on the website of the Fondazione SanRaffaele del Monte Tabor - Milano
- ^ Jean-Laurent Casanova on the website of the Robert Koch Foundation
| personal data | |
|---|---|
| SURNAME | Casanova, Jean-Laurent |
| BRIEF DESCRIPTION | French medic (pediatric immunology) |
| DATE OF BIRTH | June 14, 1963 |
| PLACE OF BIRTH | Paris |