John Sutherland (chemist)

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John Sutherland, 2017

John D. Sutherland (born July 24, 1962 ) is a British chemist, known for investigations into the origin of life.

Sutherland studied chemistry at Oxford University (Lincoln College) with a bachelor's degree in 1984 and received his PhD with Jack Baldwin at Balliol College. He then taught at Oxford. In 1998 he became Professor of Biochemistry at Manchester University and in 2010 he joined the Medical Research Council's Molecular Biology Laboratory in Cambridge. He has been Simons' investigator since 2013.

Sutherland was able to point out a possible way of self-assembly of ribonucleotides with pyrimidine , which is used in half of the nucleobases of DNA and RNA (the other half uses purine ). He is also researching similar mechanisms for the purine-containing nucleobases and the formation of the genetic code.

In 2014 he received the Darwin Medal . In 2011 he received the Tilden Prize of the Royal Society of Chemistry and in 2009 the Max Tishler Prize at Harvard. In 2012 he and Matthew Powner won the Origin of Life Challenge, which was presented in 2011 by the Californian entrepreneur and chemist Harry Lonsdale. In 2017 Sutherland was elected to the Royal Society .

Fonts

  • with Matthew W. Powner, Beatrice Gerland: Synthesis of activated pyrimidine ribonucleotides in prebiotically plausible conditions, Nature, Volume 459, 2009, pp. 239-242. PMID 19444213 .
  • with Matthew W. Powner, JW Szostak: Chemoselective multicomponent one-pot assembly of purine precursors in water, J Am Chem Soc, Volume 24, 2010, pp. 16677-16688.
  • with Matthew W. Powner: Prebiotic chemistry: a new modus operandi, Phil. Trans. R. Soc. B, Volume 366, 2010, pp. 2870-2877
  • with BH Pate., C. Percivalle, DJ Rison, CD Duffy: Common origins of RNA, protein, and lipid precursors in a cyanosulfidic protometabolism, Nature Chemistry, Volume 7, 2013, pp. 301-307, PMID 25803468

Web links

Individual evidence

  1. Communication from the MRC Laboratory of Molecular Biology 2012