Keratohyalin

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Keratohyalin
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Keratohyalin is a chemically not precisely defined protein that occurs in keratohyalin granules in epithelial cells of the skin .

properties

Keratohyalin is accumulated in the keratinization in the grain ( Stratum granulosum ) and prickly cell ( Stratum spinosum ) of epithelia in the form of small grains ( granules ) within the cells . Keratohyalin does not contain any sulfhydryl groups or disulfide bridges . In the course of further cornification, it is converted into eleidin and finally into keratin . The keratin is transported into the stratum lucidum , which is why this layer appears as a very thin line. It serves to protect against water loss.

literature

  • Thieme pocket textbook histology, Renate Lüllmann-Rauch, 2nd edition