Klaus Pätau

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Klaus Pätau , in the Anglo-Saxon-speaking area Klaus Patau , (born September 30, 1908 in Gelsenkirchen , † November 30, 1975 in Madison , Wisconsin ) was a German-American human geneticist .

Life

Pätau received his doctorate from Friedrich Wilhelms University in 1936 . With the help of a grant from the Rockefeller Foundation , he went to the John Innes Horticultural Institution in Merton Park, Surrey for one year in 1938 . From 1939 he was an assistant in Max Hartmann's department at the Kaiser Wilhelm Institute for Biology in Berlin-Dahlem . After the Second World War he was from 1946 assistant to Hans Nachtsheim at the Institute for Genetics at Berlin University . Finally, in 1948, after a six-month stay at the Institute of Animal Genetics at the University of Edinburgh , he moved to the USA, where he researched and taught at the University of Wisconsin in Madison until his death .

In his early genetic work, Klaus Pätau examined the chromosomes of two species of fruit flies and a spider . He is one of the pioneers of microscope photometry ; but his two-wavelength method found no use in quantitative cytogenetics . In 1960 he first described the Patau syndrome, later named after him, as a result of a trisomy of human chromosome 13 or parts of it.

He was married to Eeva Therman since 1961.

Publications (selection)

  • Klaus Pätau: The mathematical analysis of the evolutionary processes. In: Z Indukt Stamm Vererbungsl 76/1939, pp. 220-228.
  • Klaus Pätau: A new χ² board . In: Z Vererbungsl 80/1942, pp. 558-564.
  • Klaus Pätau: The exchange of factors: Its cytological basis and its meaning. In: Jena Z Med Naturwiss 78/1947, pp. 163–181.
  • Klaus Patau, Hewson Swift : The DNA-content (Feulgen) of nuclei during mitosis in a root tip of onion. In: Chromosoma 6/1953, pp. 149-169.
  • D Srinivasachar, Klaus Patau: Proportionality between nuclear DNA-content and Feulgen dye-content. In: Exp Cell Res 17/1959, pp. 286-298.
  • Klaus Patau, D Srinivasachar: A microspectrophotometer for measuring the DNA content of nuclei by the two wave length method. In: Cytologia 25/1960, pp. 145-151.
  • Klaus Patau: The identification of individual chromosomes, especially in man. In: Am J Hum Genet 12/1960, pp. 250-276.
  • Klaus Patau, Eeva Therman, David W Smith, RI Demars: Trisomy for chromosome No. 18 in man. In: Chromosoma 12/1961, pp. 280-285.
  • Klaus Patau: The origin of chromosomal abnormalities. In: Pathol Biol (Paris) 11/1963, pp. 1163-1170.
  • Klaus Patau: Identification of chromosomes. In: JJ Yunis (ed): Human chromosome methodology. Academic, New York 1965, pp. 155-186.
  • John Marius Opitz , Klaus Patau: A partial trisomy 5p syndrome. In: Birth Defects 11/1975, pp. 191-200.

Web links

Humboldt-UB → Catalog search: Klaus Patau and Pätau

Individual evidence

  1. ↑ Klaus Pätau: Chromosome morphology in Drosophila melanogaster and Drosophila simulans and their genetic significance. In: Naturw 23/1935, pp. 537-543.
  2. ^ Klaus Patau: X - segregation and heterochromasy in the spider Aranea reaumuri. In: Heredity 2/1948, pp. 77-100.
  3. ↑ Klaus Patau: Absorption microphotometry of irregular-shaped objects. In: Chromosoma 5/1952, pp. 341-362.
  4. ↑ Klaus Patau, David W Smith, Eeva Therman, Stanley L Inhorn, HP Wagner: Multiple congenital anomaly caused by an extra autosome. In: Lancet 1/1960 (7128), pp. 790-7933.
  5. ↑ Crow James F, Laxova Renata, Susman Millard: Memorial resolution of the faculty of the University of Wisconsin – Madison on the death of professor emerita Eeva Therman Patau. Faculty document 1845, Madison, April 4, 2005.
personal data
SURNAME Patau, Klaus
ALTERNATIVE NAMES Patau, Klaus
BRIEF DESCRIPTION German-American human geneticist
DATE OF BIRTH September 30, 1908
PLACE OF BIRTH Gelsenkirchen
DATE OF DEATH November 30, 1975
Place of death Madison (Wisconsin)