Conjugated protein

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The heme- conjugated protein hemoglobin with four differently colored subunits

A conjugated protein (also known as heteroprotein or proteid ) is a protein that has bound another non- protein molecule. In contrast, multimeric proteins consist of several protein components.

properties

Conjugated proteins are e.g. B. lipoproteins , glycoproteins , phosphoproteins , heme proteins , flavoproteins , ribonucleoproteins , metalloproteins , phytochromes , cytochromes and opsins . The non-protein portion of a conjugated protein can be a post-translational modification or a prosthetic group .

As part of a molecular marker can in vitro be conjugated molecules with different proteins.

literature

  • David L. Nelson, Michael M. Cox: Lehninger Biochemie . 4th edition. Springer, Berlin / Heidelberg 2009, ISBN 978-3-540-68637-8 .

Individual evidence

  1. ↑ G. Wald: CAROTENOIDS AND THE VISUAL CYCLE. In: The Journal of general physiology. Volume 19, Number 2, November 1935, pp. 351-371, PMID 19872932 . PMC 2141433 (free full text).
  2. ↑ D. Pfister, M. Morbidelli: Process for protein PEGylation. In: Journal of controlled release: official journal of the Controlled Release Society. Volume 180, April 2014, pp. 134–149, doi : 10.1016 / j.jconrel.2014.02.002 . PMID 24531008 .