Krukenberg tumor
Classification according to ICD-10 | |
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C79 | Secondary malignant neoplasm in other locations |
ICD-10 online (WHO version 2019) |
The Krukenberg tumor ( Fibrosarcoma ovarii mucocellulare carcinomatodes ) was named after Friedrich Ernst Krukenberg (1871-1946), who first described it. This tumor represents a special form of ovarian metastases . 10 to 15% of malignancies of the ovary are metastases . The Krukenberg tumor is an often bilateral, cavitary metastasis (drained metastasis in the peritoneal space ) of a signet ring cell carcinoma of the gastric mucosa. Histologically, there is a typical picture with mucus-forming signet ring cells. The ovarian stroma proliferates profusely and the cells multiply.
In individual cases, hyperestrogenism or virilization can follow.
literature
- U. Riede among others: General and special pathology. Verlag Thieme, Stuttgart 2004. 5th edition. ISBN 978-3-13-683305-6
- FE Krukenberg: About the fibrosarcoma ovarii mucocellulare (carcinomatodes). Archive for Gynecology, Berlin, Volume 50, 1896, pp. 287–321.
- P. Khurana, R. Sachdev, S. Uppal, D. Bisaria: Krukenberg tumor in a 13-year-old girl: a rare occurrence. In: Indian journal of pathology & microbiology Volume 53, Number 4, 2010 Oct-Dec, pp. 874-875, ISSN 0974-5130 . doi : 10.4103 / 0377-4929.72024 . PMID 21045460 .
- SV Sakpal, N. Babel, R. Pulinthanathu, TR Denehy, RS Chamberlain: Krukenberg tumor: metastasis of Meckel's diverticular adenocarcinoma to ovaries. In: Journal of Nippon Medical School = Nihon Ika Daigaku zasshi Volume 76, Number 2, April 2009, pp. 96-102, ISSN 1345-4676 . PMID 19443995 . (Review).
- OM Al-Agha, AD Nicastri: An in-depth look at Krukenberg tumor: an overview. In: Archives of Pathology & Laboratory Medicine , Volume 130, Number 11, November 2006, pp. 1725-1730, ISSN 1543-2165 . PMID 17076540 . (Review).